肿瘤药学2018，Vol.8Issue(1)：60-63,4.DOI:10.3969/j.issn.2095-1264.2018.01.14
右美托咪定对结肠癌术后胃肠功能恢复的影响
The Effect of Dexmedetomidine on Gastrointestinal Function of Patients with Colorectal Cancer after Operation
苑汐子 1党长宁 1孙凤伟 1王永 1张喻然1
作者信息
- 1. 辽宁中医药大学附属三院 肛肠五科,辽宁 沈阳,110000
- 折叠
摘要
Abstract
Objective To investigate the effect of dexmedetomidine on postoperative gastrointestinal function recovery in colon cancer. Methods 88 patients with colorectal cancer were randomly divided into two groups: control group (n=40) and control group (n=40). The pa-tients in control group were treated with conventional anti-infection, would dressing, postoperative drainage and other treatment, the patients in observation group were given continuous intravenous infusion of dexmedetomidine for 48 hours on the basis of treatment on control group, Gastrointestinal function returned to normal time, interventional TNF-α, hs-CRP levels, and the gastrointestinal related complications were compared between the two groups. Results The levels of norepinephrine and adrenaline in the observation group were lower than those in the control group (P<0.05). The levels of TNF-α and hs-CRP in the observation group were lower than those in the control group (P<0.05). The ratio of intestinal obstruction, bloating, abdominal pain and gastrointestinal peristalsis in the observation group were significantly higher than these of the control group (P<0.05). The time of defecation in the observation group was longer than that in the control group (P<0.05). Conclusion The use of dexmedetomidine in colorectal cancer can reduce the secretion of catechu and the inflammatory response of the body, thus promote the recovery of gastrointestinal function and reduce the complications of gastrointestinal tract.关键词
右美托咪定/结肠癌/胃肠功能Key words
Dexmedetomidine/Colon cancer/Gastrointestinal function分类
医药卫生引用本文复制引用
苑汐子,党长宁,孙凤伟,王永,张喻然..右美托咪定对结肠癌术后胃肠功能恢复的影响[J].肿瘤药学,2018,8(1):60-63,4.
