肿瘤药学2018，Vol.8Issue(1)：112-116,5.DOI:10.3969/j.issn.2095-1264.2018.01.26
临床药师参与治疗胃癌患者耐碳青霉烯类的肠杆菌科细菌重症感染的实践
Participation of Clinical Pharmacists for the Treatment of Gastric Cancer Patient with Severe Infection Caused by CRE
摘要
Abstract
Objective To explore the effective treatment of CRE infection. Methods Clinical pharmacists involved in the implementa-tion process and pharmaceutical care for the treatment of intra-abdominal infection and septicemia in gastric cancer patient caused by CRE, which made treatment repeatedly. Results The patients adjusted the anti-infection regimen many times, including Meropenem combined with fosfomycin, Tigecycline combined with amikacin, but the treatment effect is poor. When Clinical pharmacists change the anti-infection program for imipenem combined with aztreonam, and to strengthen nutrition support, the patient recovered and discharged. Conclusion The treatment of CRE severe infection should be combined regimen which is based on tigecycline or polymyxin or meropene. In this case, tigecycline and meropene combined treatment is failure. We speculate the CRE strains may product metal enzyme. And for such strains, we recommend to choose aztreonam combined treatment.关键词
耐碳青霉烯类肠杆菌科细菌/肠梗阻术后/腹腔感染/败血症/临床药师Key words
Carbapenem-resistant Enterobacteriaceae/intestines abstruction postoperative/intra-abdominal infection/septicemia/Clinical pharmacists.分类
医药卫生引用本文复制引用
何鸽飞,孙吉,肖群林,刘晓慧,凌丽芬..临床药师参与治疗胃癌患者耐碳青霉烯类的肠杆菌科细菌重症感染的实践[J].肿瘤药学,2018,8(1):112-116,5.基金项目
湖南省自然科学基金项目(2017JJ2285). （2017JJ2285）
