中山大学学报（医学科学版）2018，Vol.39Issue(1)：82-86,5.
GRACE评分对急性胸痛患者30d心血管不良事件的预测价值
Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain
摘要
Abstract
[Objective]To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients.[Methods]A prospective,observational analysis was conducted in the patients with acute chest pain in Emergency Department(ED)from January 1,2016 through April 1,2016.Data including characteris-tics and GRACE scores were collected.All causes leading to MACE were followed up at 30th day after the onset of acute chest pain.[Results]Among a total of 209 patients presenting with acute chest pain enrolled in this study,110 were male (52.63%)and 99 were female(47.37%).The range of age was 20-98years old,and mean age was(65.28±16.85)years old.During follow-up period,12 patients had MACE,2 patients died in ED,3 patients died in hospital,6 patients died out of hospital,and 1 person was diagnosed with myocardial infarction. When compared with non-MACE group,factors including age,BMI,hospitalized patient number,and number of patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group(P<0.05). The predictive ROC curve area of GRACE scores in 30-day MACE was 0.819(0.735 to 0.902). The optimal sensitivity and specificity were 0.92 and 0.65,respectively. The probability of 30-day cardiovascular adverse events in various GRACE score risk stratification was 0.95%(low-risk),6.67%(medi-um-risk),and 18.92%(high-risk),respectively.[Conclusion]The GRACE score was a useful predictor to the occur-rence of 30-day cardiovascular adverse events in acute chest pain patients.关键词
GRACE评分/急性胸痛/危险分层/心血管不良事件Key words
GRACE scores/acute chest pain/risk stratification/cardiovascular adverse events分类
医药卫生引用本文复制引用
黄振华,詹红,廖瑾莉,肖孝勇,叶子,蒋鹏,陈伟栋,熊艳,杨震,曾庆理..GRACE评分对急性胸痛患者30d心血管不良事件的预测价值[J].中山大学学报（医学科学版）,2018,39(1):82-86,5.基金项目
国家自然科学基金面上项目(81670220) （81670220）
广东省医学科学技术研究基金(B2014110) （B2014110）
广东省科技计划项目(2014A020212150) （2014A020212150）
