组织工程与重建外科杂志2018，Vol.14Issue(1)：39-42,4.DOI:10.3969/j.issn.1673-0364.2018.01.011
组织工程组织血管化的研究进展
Research Progress of Vascularization Within Engineered Tissues
摘要
Abstract
The reconstruction of tissue and organ by tissue engineering is one of the potential treatments for the tissue defect and organ failure. The current main problem of tissue engineering is how to build the blood supply timely after engineered tissue implantation to avoid shrinkage or failed tissue function. The recent literature about the vascularization of engineered tissues was extensively reviewed and divided up into four parts: the modification of scaffold, addition of cells, addition of angiogenic factors or gene therapy, in vitro or in vivo prevascularization, according to the difference of vascularization strategies. The advantages and limitations of various kinds of vascularization strategies were analyzed. Furthermore,the future development direction was put forward.关键词
组织工程/血管化/支架材料/血管生成因子/轴心血管Key words
Tissue engineering/Vascularization/Scaffold/Angiogenic factor/Axial vessel分类
生物科学引用本文复制引用
贾智明,郭海林,陈方..组织工程组织血管化的研究进展[J].组织工程与重建外科杂志,2018,14(1):39-42,4.基金项目
国家自然科学基金资助项目(81470911). （81470911）
