老年医学与保健2018，Vol.24Issue(1)：37-40,4.
右归胶囊治疗绝经后女性下肢动脉粥样硬化的临床疗效观察
Clinical Effect of Yougui Capsule on Lower Extremity Atherosclerotic Disease in Postmenopausal Women
孙璐 1陈基敏 1陈咸川 1吴晨 1谢吟灵1
作者信息
- 1. 上海中医药大学附属岳阳中西医结合医院老年科,上海200437
- 折叠
摘要
Abstract
Objective To observe the clinical effect of Yougui capsule on lower extremity atherosclerotic disease (LEAD) in postmenopausal women.Methods 64 postmenopausal women,aged from 60 to 95 with the average of (72.8± 10.5) years,were randomly divided into 2 groups:observation group and experiment group,32 in each;general treatment plus oral administration of cilostazol capsules (50 mg once,twice a day) was performed on all the patients in both groups while oral administration of Yougui capsules (1.8 g once,3 times a day) was added to patients in experiment group;the courses in the 2 groups both lasted for 12 weeks;the detections ofestradiol (E2) and ankle brachial index (ABI) were made before and after treatment respectively and TCM syndrome scores were evaluated.Results Before treatment,there existed no statistical difference in ABI between the 2 groups;after treatment,no improvement in ABI in observation group;ABI in experiment group after treatment was statistically different from that before treatment [(0.52±0.06) vs (0.73±0.08),P＜0.05] and was superior to that in observation group [(0.73 ±0.08) vs (0.57±0.07),P＜ 0.05];before treatment,E2 of all the patients in both groups were under 20 pg/mL while,after treatment,E2 of the patients in experiment group increased and was superior to that of the paitents in observation group (84.34 ％ vs 0 ％,P ＜ 0.01);after treatment,the total effective rate in experiment group was higher than that in observation group (87.5％ vs 43.8％,P＜0.01).Conclusions Yougui capsules can increase the level of E2 in postmenopausal women,raise ABI and improve the TCM syndrome scores of LEAD.关键词
绝经后期/动脉粥样硬化/踝臂指数/雌二醇/右归丸Key words
postmenopause/atherosclerosis/ankle brachial index (ABI)/estradiol (E2)/Yougui capsule引用本文复制引用
孙璐,陈基敏,陈咸川,吴晨,谢吟灵..右归胶囊治疗绝经后女性下肢动脉粥样硬化的临床疗效观察[J].老年医学与保健,2018,24(1):37-40,4.
