实用肝脏病杂志2018，Vol.21Issue(2)：225-228,4.DOI:10.3969/j.issn.1672-5069.2018.02.017
94例不明原因肝功能异常患者临床与肝组织病理学分析
Clinicopathological analysis of 94 patients with unexplained abnormal liver function tests
摘要
Abstract
Objective To investigate the etiology of patients with unexplained abnormal liver function tests. Methods Ninety-four out of 2195 patients with abnormal liver function tests were recruited in this study. The blood biochemical parameters,serology,virology,abdominal imaging and liver biopsy were performed routinely. Results The diagnosis included non-alcoholic fatty liver disease(NAFLD)in 40 case(42.6%),autoimmune liver disease(AIH and PBC)in 22(23.4%),drug-induced liver injury(DILI)in 20(21.3%),and other diseases were occult chronic hepatitis B in 3(3.2%),and benign recurrent cholestasis,Wilson's disease,hemochromatosis, lymphoma,cytomegalovirus infection,dysfunction of sphincter of Oddi(SOD),Kwashiorkor syndrome and muscular dystrophy in 1 of them,and 1 still with unknown etiology. Conclusion NAFLD,ALD and DILI are the most common causes of patients with unexplained abnormal liver function tests. Genetic metabolic and other rare diseases also account for a certain proportion,which the clinicians should take attention in clinical practice.关键词
肝功能异常/病因/诊断/肝活检Key words
Abnormal liver function/Etiology/Diagnosis/Liver biopsy引用本文复制引用
汪佩文,董育玮,李郑红,姜海琼,陆伦根..94例不明原因肝功能异常患者临床与肝组织病理学分析[J].实用肝脏病杂志,2018,21(2):225-228,4.基金项目
国家自然科学基金项目(编号:81070345,81300326) （编号:81070345,81300326）
