畜牧兽医学报2017，Vol.48Issue(11)：2023-2033,11.DOI:10.11843/j.issn.0366-6964.2017.11.003
细菌主要外排泵及其调控蛋白研究进展
Research Progress of the Mainly Bacterial Efflux Pumps and Related Regulator
摘要
Abstract
Multidrug efflux pumps are found in any organism and constitute a series of transporters,which contribute to the resistant to antibiotics intrinsic and acquired.Nowadays,numerous efflux pump-related proteins have been investigated,and the exact mechanism of induction drug extrusion is researching.Also,there are few efflux-related protein used in antibiotic residue detection.The aim of this review is to elucidate the types of efflux pumps and their constitutive and regulator proteins,and also the application of efflux pump proteins in antibiotic residue detection.Finally,the problems and developmental trends in the research of efflux pump are summarized and discussed.关键词
抗生素/外排泵/组成蛋白/调节蛋白/残留检测Key words
antibiotics/efflux pump/constitutive protein/regulator protein/residue detection分类
农业科技引用本文复制引用
高海娇,程古月,王玉莲,宁佳囡,陈婷,李俊,郝海红,袁宗辉..细菌主要外排泵及其调控蛋白研究进展[J].畜牧兽医学报,2017,48(11):2023-2033,11.基金项目
国家重点研发计划(2016YFD0501302 （）
2017YFD0501406) （）
国家自然科学基金(31772791 （）
31502115) （）
中央高校基础研究基金(2662015PY035) （2662015PY035）
国家畜禽产品质量安全风险评估(GJFP2016008) （GJFP2016008）
华中农业大学博士科研创新项目(2014bs14) （2014bs14）
