中国感染控制杂志2018，Vol.17Issue(2)：103-106,4.DOI:10.3969/j.issn.1671-9638.2018.02.003
2013-2016年老年病医院鲍曼不动杆菌临床分布及耐药性
Distribution and antimicrobial resistance of Acinetobacter baumannii in a geriatric hospital from 2013 to 2016
摘要
Abstract
Objective To analyze the clinical distribution and antimicrobial resistance change trend of Acinetobacter baumannii(AB) from a geriatric hospital in 2013-2016.Methods Specimen source,department distribution,and antimicrobial resistance of AB isolated from all patients in the hospital from 2013 to 2016 were analyzed retrospectively.Results From 2013 to 2016,1 712 strains of AB were isolated,AB isolation rates in 2013,2014,2015,and 2016 decreased year by year,which were 17.92％,17.17％,15.10％,and 11.81％,respectively.AB were mainly isolated from sputum (n =1 524,89.02％),followed by urine (n =79,4.61％) and blood (n=37,2.16％).The main departments of AB isolation were intensive care unit (n =798,46.61％),department of respiratory medicine (n =507,29.62％),and neurology department (n =156,9.11％).Resistance rates of AB to most antimicrobial agents increased in 2013-2016,resistance rates to compound sulfamethoxazole were low (25.68 ％-65.89 ％),followed by resistance rates to cefoperazone/sulbactam (54.74％-68.00％),resistance rates to imipenem were 71.40％-77.42％,to the other antimicrobial agents were all＞60％;in 2013-2016,resistance rates of AB to cefepime,cefoperazone/sulbactam,gentamicin,tobramycin,and compound sulfamethoxazole were significantly different (all P＜0.05).Conclusion Antimicrobial resistance rates of AB in this hospital is increasing,it is necessary to strengthen the monitoring,promote the rational use of antimicrobial agents,and block the infection and transmission of AB in hospital.关键词
老年病医院/鲍曼不动杆菌/耐药性/抗药性,微生物/合理用药Key words
geriatric hospital/Acinetobacter baumannii/drug resistance, microbial/rational drug use分类
医药卫生引用本文复制引用
张蓉,陈倩,祝丙华,张金萍..2013-2016年老年病医院鲍曼不动杆菌临床分布及耐药性[J].中国感染控制杂志,2018,17(2):103-106,4.基金项目
医院科研基金青年项目(16YNQN09) （16YNQN09）
