中国医院用药评价与分析2018，Vol.18Issue(1)：43-45,3.DOI:10.14009/j.issn.1672-2124.2018.01.010
瑞替普酶联合低分子肝素钙治疗急性心肌梗死的疗效观察
Observation on Efficacy of Reteplase Combined with Low Molecular Weight Heparin Calcium in Treatment of Acute Myocardial Infarction
戴萍 1范正宏2
作者信息
- 1. 武汉市第一医院药剂科,湖北武汉 430022
- 2. 武汉市第一医院心内科,湖北武汉430022
- 折叠
摘要
Abstract
OBJECTIVE: To probe into the clinical efficacy of reteplase combined with low molecular weight heparin calcium in treatment of acute myocardial infarction .METHODS:104 patients with acute myocardial infarction admitted into Wuhan No .1 Hospital from Jun .2014 to Jun.2016 were selected and divided into observation group and control group via random number table , with 52 cases in each .The control group was given reteplase injection combined with heparin sodium injection , while the observation group was given reteplase combined with low molecular weight heparin calcium for injection .Clinical efficacy , clinical indices and incidences of complications of two groups were observed .RESULTS:The total effective rates of observation group and control group were respectively 92.31％(48/52) and 88.46％(46/52), the difference had no statistical significance (P>0.05); the relief time of chest pain and 50％fall back time of ST segment of observation group were significantly shorter than those of the control group , with statistically significant differences ( P<0.05 );there was no statistical significance in the difference of the recanalization rate of vessel with 12 h between two groups ( P>0.05 ); the incidence of complications of observation group ( 9.62％, 5/52 ) was significantly lower than that of the control group ( 25.00％, 13/52 ) , with statistically significant difference ( P <0.05 ) .CONCLUSIONS: The efficacy of reteplase combined with low molecular weight heparin calcium in treatment of acute myocardial infarction is remarkable , which can significantly improve patients ' symptoms, with few complications and high safety .关键词
瑞替普酶/低分子肝素钙/急性心肌梗死Key words
Reteplase/Low molecular weight heparin calcium/Acute myocardial infarction分类
医药卫生引用本文复制引用
戴萍,范正宏..瑞替普酶联合低分子肝素钙治疗急性心肌梗死的疗效观察[J].中国医院用药评价与分析,2018,18(1):43-45,3.
