中国医院用药评价与分析2018，Vol.18Issue(1)：62-63,65,3.DOI:10.14009/j.issn.1672-2124.2018.01.018
醋酸戈舍瑞林缓释植入剂联合腹腔镜手术治疗子宫内膜异位症合并不育症的疗效观察
Observation on Efficacy of Goserelin Acetate Sustain-Release Implants Combined with Laparoscopic Surgery in Treatment of Endometriosis Complicated with Infertility
陈灵灵 1欧阳娟1
作者信息
- 1. 上海市东方医院吉安医院妇产科,江西吉安 343000
- 折叠
摘要
Abstract
OBJECTIVE: To probe into the efficacy of goserelin acetate sustain-release implants combined with laparoscopic surgery in treatment of endometriosis complicated with infertility .METHODS: 200 patients with endo-metriosis complicated with infertility admitted into Ji 'an Hospital of Shanghai Dongfang Hospital from Jun .2014 to Jun. 2016 were selected and divided into observation group and control group via random number table , with 100 cases in each.The control group was treated with laparoscopic surgery , while the observation group was given goserelin acetate sustain-release implants based on the control group .Clinical efficacy , incidences of relapse , pregnancy , improvements of symptoms and physical signs of two groups were observed .RESULTS: The total effective rate of observation group (87％, 87/100) was significantly higher than that of the control group (62％, 62/100);within the 1-year follow-up, the incidences of relapse and pregnancy of observation group were respectively 9％(9/100) and 68％(68/100), which were significantly better than those of the control group ( 35％, 35/100;32％, 32/100 ) , with statistically significant differences ( P<0.05);the clinical symptoms and physical signs of both groups were significantly improved than those of before treatment, with statistically significant differences (P<0.05), while no statistical significances were found in the differences between the two groups ( P >0.05 ) .CONCLUSIONS: The efficacy of goserelin acetate sustain-release implants combined with laparoscopic surgery in treatment of endometriosis complicated with infertility is remarkable , which can significantly reduce the incidence of relapse and improve pregnancy .关键词
腹腔镜手术/醋酸戈舍瑞林缓释植入剂/子宫内膜异位症合并不育症Key words
Laparoscopic surgery/Goserelin acetate sustained-release implants/Endometriosis complicated with infertility分类
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陈灵灵,欧阳娟..醋酸戈舍瑞林缓释植入剂联合腹腔镜手术治疗子宫内膜异位症合并不育症的疗效观察[J].中国医院用药评价与分析,2018,18(1):62-63,65,3.
