中国医院用药评价与分析2018，Vol.18Issue(2)：248-250,3.DOI:10.14009/j.issn.1672-2124.2018.02.033
150例围产期缺铁性贫血应用生血宁片致不良反应报告
Reports on 150 Cases of Adverse Drug Reactions Induced by Shengxuening Tablets in Treatment of Iron Deficiency Anemia in Perinatal Period
摘要
Abstract
OBJECTIVE: To investigate the rules and characteristics of adverse drug reactions ( ADR) induced by Shengxuening tablets in treatment of iron deficiency anemia in perinatal period , so as to provide reference for the safety drug application in clinic .METHODS:Retrospective analysis was conducted on data of ADR induced by Shengxuening tablets in treatment of iron deficiency anemia in perinatal period in Shenzhen Luohu District Maternal and Child Health Care Hospital from Jul .2015 to May 2017 in terms of the general data , patients ' age, ADR-inducing administration time, ADR involved organs and ( or ) systems and major clinical manifestations , etc.RESULTS: Of the 150 cases of ADR, there were 32 cases in Jul.-Dec.2015, accounting for 21.33％;and 63 cases in 2016, accounting for 42.00％;and 55 cases in Jan.-May 2017, accounting for 36.67％.The patients were aged within 22-38 years old, and patients aged 25-30 years old with ADR took the lead .ADR cases mostly occurred after 30 d of taking Shengxuening tablets , followed by administration of 2-3 d.ADR mainly involved digestive system , performed as constipation , changes of fecal character ( black or brown );there were no severe ADR , all patients were general ADR .CONCLUSIONS:ADR can be easily induced by Shengxuening tablets in treatment of iron deficiency anemia in perinatal period .The clinicians should apply Shengxuening tablets in an safety and effective way , and strengthen the ADR monitoring .关键词
生血宁片/缺铁性贫血/不良反应/围产期Key words
Shengxuening tablets/Iron deficiency anemia/Adverse drug reactions/Perinatal period分类
医药卫生引用本文复制引用
陈婷,张秋萍,龚善初,吴艳华,霍霞..150例围产期缺铁性贫血应用生血宁片致不良反应报告[J].中国医院用药评价与分析,2018,18(2):248-250,3.基金项目
深圳市罗湖区教育、卫生系统软科学研究计划项目(No.2015-25) （No.2015-25）
