植物学报2018，Vol.53Issue(1)：1-4,4.DOI:10.11983/CBB17234
“先驱”转录因子LEC1在早期胚胎重置春化状态的机制
Mechanism of The “Pioneer” Transcription Factor LEC1 in Resetting Vernalized State in Early Embryos
许淑娟 1种康2
作者信息
- 1. 中国科学院植物研究所,植物分子生理学重点实验室,北京100093
- 2. 中国科学院大学,北京100049
- 折叠
摘要
Abstract
Flowering is an important process for plants to switch from vegetative to reproductive phase.Vernalization is a process whereby plants acquire the ability to flower after exposure to a prolonged cold temperature.In Arabidopsis,inhibitor-type transcription factor FLOWERING LOCUS C (FLC) is a critical point in vernalization-mediated flowering pathway.Previous studies in Arabidopsis thaliana revealed that two homologous epigenome readers,VAL1 and VAL2,recognize a cis DNA element in the nucleation region for Polycomb group (PcG) silencing at the key floral repressor FLC,engaging Polycomb group proteins to induce epigenetic silencing of FLC by histone 3 lysine trimethylation (H3K27me3) during vernalization.This silencing is maintained in subsequent growth and development under normal temperature,namely vernalization memory.How to delete vernalization memory in the next generation to de novo activate FLC expression,preventing the offspring from flowering before or during winter,is not clear.Recently,Chinese scientist have found that a seed-specific transcription factor LEAFY COTYLEDON1 (LEC1) functions in deleting vernalization memory and reactivating the expression of FLC in the pro-embryo by resetting the chromatin states from the silenced state (marked by H3K27me3) to an active state (H3K36me3).This study provides important understanding of molecular and genetic mechanisms for flowering control by vernalization,and a novel strategy to genetically manipulate crop flowering times for the benefit of agricultural production,which is a great breakthrough of this field.关键词
染色体重塑/表观调控/春化作用/春化记忆Key words
chromatin reprogramming/epigenetic regulation/vernalization/vernalization memory引用本文复制引用
许淑娟,种康..“先驱”转录因子LEC1在早期胚胎重置春化状态的机制[J].植物学报,2018,53(1):1-4,4.
