国际医药卫生导报2018，Vol.24Issue(3)：382-385,4.DOI:10.3760/cma.j.issn.1007-1245.2018.03.026
盐酸右美托咪定在扁桃体切除术中的麻醉效果及对术后认知功能的影响分析
Analysis of the anesthetic effect of dexmedetomidine hydrochloride in tonsillectomy and its effect on postoperative cognitive function
摘要
Abstract
Objective To study the anesthetic effect of dexmedetomidine hydrochloride in tonsillectomy and its effect on postoperative cognitive function. Methods 100 cases of tonsil diseases from E.N.T. department of our hospital from January 2015 to January 2017 were selected and were divided into observation group and control group according to the random number table, 50 cases in each group. The control group received conventional anesthetic methods, and the observation group received dexmedetomidine hydrochloride anesthesia. The anesthetic effect of the two groups were compared and the effect of dexmedetomidine hydrochloride on postoperative cognitive function of the patients was analyzed. Results The dosage of propofol in the observation group was less than that in the control group [(73.51±8.45)mg vs.(111.75±9.67)mg], the score of agitation in the observation group was lower than that in the control group [(1.05±0.37) vs.(2.67±0.76)] (P<0.05). Postoperative 1 d MMSE score of the observation group was higher than that of the control group [(25.64±2.37) vs.(22.02±1.02)] (P<0.05). The recovery time of extubation, breathing, and consciousness of the observation group were (16.57±3.51)min, (10.34±3.48)min, (12.24±3.43)min, shorter than those of the control group (P<0.05). Conclusion The application of dexmedetomidine hydrochloride anesthesia in tonsillectomy helps to improve the anesthetic effect, improve postoperative cognitive function in patients, reduce restlessness after anesthesia, ensure the safety of operation.关键词
盐酸右美托咪定/扁桃体切除术/麻醉效果/认知功能Key words
Dexmedetomidine hydrochloride/Tonsillectomy/Anesthetic effect/Cognitive function引用本文复制引用
郑德强,邬文伟,刘炯峰..盐酸右美托咪定在扁桃体切除术中的麻醉效果及对术后认知功能的影响分析[J].国际医药卫生导报,2018,24(3):382-385,4.
