河北医学2018，Vol.24Issue(2)：197-201,5.DOI:10.3969/j.issn.1006-6233.2018.02.005
维持性血液透析患者血镁水平与心脏瓣膜钙化的关系
Relationship between Blood Magnesium Level and Cardiac Valve Calcification in Maintenance Hemodialysis Patients
摘要
Abstract
Objective:To explore the relation between serum magnesium and cardiar valve calcification (CVC) in maintenance hemodialysis(MHD) patients. Methods: Patients with age≥18 years old,mainte-nance hemodialysis for≥3 months were enrolled in this study.We collected their clinical data and blood bio-chemical indexes,CVC was measured by echocardiography. Logistic regression was used to analyze the relation between serum magnesium and CVC. Results:①Among 149 MHD patients,serum magnesium average was 1. 08±0.16mmol/L and 100 cases were high serum magnesium (67.1%),49 cases were normal serum magnesi-um(32.9%).98 cases were with CVC (65.8%). There were 60 cases with CVC (60.0%) in the high blood magnesium group,which were significantly lower than those 38 with CVC in the normal serum magnesium. ②Age,dialysis age,coronary heart disease, correction of calcium and serum scale were significantly higher in CVC group than non-CVC group(P <0.05). Serum magnesium level and the incidence of high serum magne-sium were significantly higher in non-CVC group than CVC group (P <0.05). ③Logistic regression analysis dispaly:Serum magnesium was independent negatively associated with CVC (P = 0.001); age, dialysis age,serum phosphorus were independent positively associated with CVC (P<0.05). Serum magnesium was independently negatively associated with MVC,AVC,MVC and AVC (P<0.05). Serum phosphorus was inde-pendently positively associated with MVC,AVC,MVC and AVC (P<0.05). Dialysis age was independently positively associated with MVC (P<0.05). Age was independently positively associated with AVC (P<0.001). Conclusion: The higher prevalence of serum magnesium, the higher serum magnesium and CVC in MHD patients,high serum magnesium can reduce the incidence of CVC in MHD patients; high serum phos-phorus is an independent risk factor for CVC.关键词
血清镁/血液透析/心脏瓣膜/钙化Key words
Serum magnesium/Hemodialysis/Cardiar valve/Calcification引用本文复制引用
申抗抗,王景福,张宝红,段书众,吴艳青..维持性血液透析患者血镁水平与心脏瓣膜钙化的关系[J].河北医学,2018,24(2):197-201,5.基金项目
河北省承德市科学技术局计划项目,(编号:20142071) （编号:20142071）
