河北医学2018，Vol.24Issue(2)：255-258,4.DOI:10.3969/j.issn.1006-6233.2018.02.020
缺血预适应和侧枝循环对合并糖尿病的急性心肌梗死患者近期预后的影响
Effects of Ischemic Preconditioning and Collateral Circulation on Short-term Prognosis in Patients with Acute Myocardial Infarction Complicated with Diabetes Mellitus
摘要
Abstract
Objective:To investigate the effects of myocardial ischemic preconditioning (IP) and coro-nary collateral circulation (CR) on the short-term prognosis of patients with acute myocardial infarction (AMI) complicated with diabetes mellitus. Methods: Retrospective analysis of diabetic patients with acute myocardial infarction in 115 cases,according to the 48 hours of pre infarction angina pectoris divided into is-chemic preconditioning group (IP group,n=69) and non-ischemic preconditioning group (group NIP, n=46). The two groups were divided into subgroups (A group, B group, C group, D group) according to the collateral circulation(CR). The baseline data,myocardial infarct size,left ventricular ejection fraction and 6 months follow-up. The incidence of death,severe arrhythmia,left ventricular function and other adverse re-actions were compared between the two groups. Results:The peak value of CK and CK-MB in group A were significantly lower than that in group D(P<0.05). The A in group LVEF was significantly higher than that in other groups(P<0.05). Incidence of adverse reactions of A group was lower than that of B group,C group,D group (P<0.05);B group,C group of patients with adverse reaction rate was significantly lower than that in D group,the difference was statistically significant(P<0.05).Conclusions:In patients with acute myocardial infarction complicated with diabetes mellitus, myocardial ischemic preconditioning and collateral circulation can play a protective role in myocardial infarction and improve the prognosis.关键词
心肌缺血预适应/急性心肌梗死/侧枝循环Key words
Myocardial ischemic preconditioning/Acute myocardial infarction/Collateral circu-lation引用本文复制引用
张俊义,赵凯迪,马颖,延荣强,于忠详..缺血预适应和侧枝循环对合并糖尿病的急性心肌梗死患者近期预后的影响[J].河北医学,2018,24(2):255-258,4.基金项目
山东省卫生厅科研计划项目,(编号:2013WS2761) （编号:2013WS2761）
