汤金梅 1毕亭亭 1周茜 1徐晓 1乔慧瑛 1杨绪枫 1吕荣1
作者信息
- 1. 南通大学附属吴江医院老年医学科, 江苏 苏州 215200
- 折叠
摘要
Abstract
Objective:To investigate and compare predictive diagnostic value of TG/HDL-C,TC/HDL-C,non-HDL-C ratios for isolated post-challenge hyperglycemia (IPH). Methods:220 patients with IPH and 216 normal glucose tolerances(NGT) were enrolled in this study.All subjects were underwent a75-g OG-TT. Their clinical,lipid and glucose were measured and calculated TG/HDL-C, TC/HDL-C, non-HDL-C ratios. Results: Compared with NGT, patients with IPH had higher blood pressure, BMI, waist circumfer-ence,TC,TG,LDL-C,TG/HDL-C, TC/HDL-C,non-HDL-C and 2h-PG, with lower HDL-C (P<0. 05). According to logistic regression analysis,after adjusted for the age,blood pressure,BMI,waist circum-ference and FBG,TC,TG,LDL-C,TC/HDL-C,TG/HDL-C,and non-HDL-C were all positively correla-ted with IPH. TG/HDL-C obtained the highest area under the curve (AUC) of 0.832 determined by ROC curves,suggesting that TG/HDL-C has the greatest diagnostic value of IPH. The cut off value of TG/ HDL-C was set at 1.42,with the sensitivity of 81.90% and the specificity of 69.20%. Conclusion:TG/HDL-C has the greatest diagnostic value of IPH,patients whose TG/HDL-C is over 1.42 need further test of OGTT in or-der to diagnose IPH earlier.关键词
血脂指标比值/单纯餐后高血糖型糖尿病/血脂异常Key words
Lipid ratios/Isolated post-challenge hyperglycemia/Dyslipidemia
