河北医学2018，Vol.24Issue(2)：305-309,5.DOI:10.3969/j.issn.1006-6233.2018.02.034
应用眼底视网膜成像系统RetcamⅢ早期诊断新生儿视网膜母细胞瘤的临床研究
Clinical Study of Retcam Ⅲ in the Diagnosis of Neonatal Retinoblastoma by Retinal Imaging System
摘要
Abstract
Objective:To analyze the clinical value of Retcam III in the early diagnosis of neonatal reti-noblastoma using retinal imaging system. Methods:A retrospective analysis was carried out from July 2014 to July 2016 in 75 cases of RB newborns in our department of Ophthalmology and 100 cases of eyes. These pa-tients were treated with binocular indirect ophthalmoscope, RetCam III and B type ultrasonic diagnosis RB. Results:100 eyes were diagnosed with a double eye ophthalmoscope for the gold standard to diagnose the AE phase of the eye condition,the use of RetCam III diagnosis in the A phase is consistent,B,C,D and E there was a small difference,but very close(P> 0.05). Through the analysis of the Kappa coefficient,the 2 kinds of RB staging are consistent,of which the Kappa coefficient was =0.9794, and the 95% confidence interval was 0.9598-0.9991. In 100 eyes,there were 58 eyes in the A-D period. Using binocular ophthalmoscope 132 standard tumor were detected by RetCam,III in the detection of tumor 130, the detection rate was 98.48%. 111 tumor bodies were detected by B type ultrasound,and the detection rate was 84.09% (P<0.05). RetCam III detection occurred in 2 cases of subconjunctival hemorrhage,the incidence rate was 2%,but there was no adverse reaction in corneal contusion,retinal hemorrhage and infection. The overall bad rate was 2%. The bin-ocular ophthalmoscope and B ultrasonic in the above adverse complications were higher,no difference (P>0. 05). This reveals that RetCam III is safe,reliable,and has good prognosis,and is worthy of clinical applica-tion. Conclusion:The early diagnosis of neonatal retinoblastoma by Retcam III (retina imaging system) can be used to diagnose the tumor staging and disease in a timely and accurate way. It has high specificity and de-tection rate,and has high diagnostic value in clinical.关键词
RetcamⅢ/视网膜母细胞瘤/新生儿/早期诊断Key words
Retcam III/Retinoblastoma/Neonatal/Early diagnosis引用本文复制引用
但艳苹,陈清冉,饶丽..应用眼底视网膜成像系统RetcamⅢ早期诊断新生儿视网膜母细胞瘤的临床研究[J].河北医学,2018,24(2):305-309,5.基金项目
湖北省十堰市科学技术研究与开发计划项目,(编号:15Y70) （编号:15Y70）
