河北医学2018，Vol.24Issue(2)：313-317,5.DOI:10.3969/j.issn.1006-6233.2018.02.036
叶酸联合维生素B12治疗老年冠心病慢性心力衰竭伴高同型半胱氨酸血症的疗效分析
Curative Effect of Folic Acid Combined with Vitamin B12in Treating Senile Coronary Heart Disease with Chronic Heart Failure and Homocysteinemia
张泽丹 1曾莉 1谭平1
作者信息
- 1. 中国人民解放军福州总医院干部保健科, 福建 福州 350025
- 折叠
摘要
Abstract
Objective:To investigate the efficacy of folic acid and vitamin B12in the treatment of elderly patients with chronic heart failure and hyperhomocysteinemia. Methods: A total of 80 elderly patients with CHD with hyperhomocysteinemia who were hospitalized from June 2015 to June 2017 were randomly divided into two groups. The patients in the control group were given symptomatic treatment while the patients in the experimental group Folic acid and vitamin B12were used to compare disease-related parameters,heart failure grade and quality of life in both groups. Results:The levels of HCY,NT-proBNP,TG,TC,LDL-C,MCP-1 and IL-8 in the experimental group were significantly lower than those in the control group (P <0.01). The NYHAⅠ ~ Ⅱlevel after treatment was significantly higher than that of the control group Group,there was a significant difference (P <0.05). Conclusion: The effect of folic acid combined with vitamin B12in the treatment of chronic heart failure and hyperhomocysteinemia in elderly patients with coronary heart disease is significant,and it is of reference significance.关键词
叶酸/维生素B12/慢性心力衰竭/高同型半胱氨酸血症Key words
Folic acid/Vitamin B12/Chronic heart failure/Hyperhomocysteinemia引用本文复制引用
张泽丹,曾莉,谭平..叶酸联合维生素B12治疗老年冠心病慢性心力衰竭伴高同型半胱氨酸血症的疗效分析[J].河北医学,2018,24(2):313-317,5.
