河北医学2018，Vol.24Issue(2)：317-321,5.DOI:10.3969/j.issn.1006-6233.2018.02.037
孟鲁司特及特布他林联用对支气管哮喘患儿的疗效及症状评分的影响
Influence of Effect and Symptom Scores of Montelukast and Terbutaline in the treatment of Children Patients with Bronchial Asthma
摘要
Abstract
Objective:To study influence of effect and symptom scores of montelukast and terbutaline in the treatment of children patients with bronchial asthma. Methods: 124 children with bronchial asthma who were treated in our hospital from June 2014 to December 2016 were enrolled in this study. The children were divided into observation group and control group with 62 cases in each group,the two groups were given rou-tine anti infection, oxygen inhalation, and relieving asthma and bronchiectasis and other related drugs. The control group was treated with terbutaline inhalation,while the observation group based on the control group of the drug,plus taking montelukast. After 2 months of treatment,the curative effect of the treatment group was compared with that of the two groups(FEV1,PEF and FEV1/FVC),symptom scores and adverse reactions. Results:The clinical control rate of the observation group was 40.32%, the total effective rate was 98.39%, which were significantly higher than the control group of 17.74% and 88.71%,the difference was statistically significant (P <0.05). After treatment,the levels of FEV1,PEF and FEV1/FVC in the two groups were sig-nificantly higher than those before treatment, the observation group was significantly higher than the control group,the difference was statistically significant(P <0.05). After treatment,the two groups were significant-ly lower than those in the control group in the day and night symptom scores, and the observation group was significantly lower than the control group,the difference was statistically significant(P < 0.05). The total in-cidence of adverse reactions in the observation group was 6.45%,compared with the control group of 11.29%, the difference was not statistically significant (P > 0.05). Conclusion: Montelukast and terbutaline in the treatment of children with bronchial asthma has a good effect, but also can effectively improve the symptom score.关键词
孟鲁司特/特布他林/支气管哮喘/疗效Key words
Montelukast/Terbutaline/Bronchial asthma/Efficacy引用本文复制引用
杨硕,洪源,党媛媛..孟鲁司特及特布他林联用对支气管哮喘患儿的疗效及症状评分的影响[J].河北医学,2018,24(2):317-321,5.基金项目
河北省唐山市科技局项目研究成果,(编号:10130277c) （编号:10130277c）
