河北医学2018，Vol.24Issue(2)：325-328,4.DOI:10.3969/j.issn.1006-6233.2018.02.039
艾司西酞普兰治疗脑卒中后抑郁及对患者神经功能认知功能的影响
The Effect of Escitalopram on the Neurologic Function and Cognitive Function of the Post-stroke Depression Patients
摘要
Abstract
Objective:To explore the effect of Ai Sciplan on the neural function and cognitive function of patients with post-stroke depression. Methods:82 stroke patients were selected in our hospital from Octo-ber 2016 to October 2017 were patients with depression as the research object,it was divided into study group ( 41 cases ) and control group ( 41 cases ) by random number table method, two groups of patients were treated with routine drug treatment the study group,patients taking escitalopram on the basis of routine thera-py,patients in control group received placebo on the basis of conventional drug treatment, continuous treat-ment for 12 weeks. The depression of two groups were compared before and after treatment, nerve function, the cognitive function and life ability The evaluation. Results: Before treatment, there was no significant difference in the HAMD score,NIHSS score,MMSE score and FIM score between the two groups(P>0.05). After treatment,the HAMD scores, NIHSS scores, MMSE scores and FIM scores of the two groups were all improved,and the observation group was significantly better than the control group (P<0.05). Conclusion:In the clinical treatment of post-stroke depression, the use of escitalopram can improve neurological function and cognitive function,as well as improve depression and viability of patients.关键词
艾司西酞普兰/脑卒中/抑郁/神经功能/认知功能Key words
Escitalopram/Cerebral apoplexy/Depression/Nerve function/Cognitive func-tion引用本文复制引用
胡会婷,王敏忠..艾司西酞普兰治疗脑卒中后抑郁及对患者神经功能认知功能的影响[J].河北医学,2018,24(2):325-328,4.基金项目
山东省卫生厅科研计划项目,(编号:2012ws1783) （编号:2012ws1783）
