解放军医学院学报2017，Vol.38Issue(12)：1106-1108,3.DOI:10.3969/j.issn.2095-5227.2017.12.004
长链非编码RNA XLOC_004122对肺结核预后的辅助诊断价值
Expression of long non-coding RNA XLOC_004122 predicts prognosis of pulmonary tuberculosis
摘要
Abstract
Objective To investigate the expression of long non-coding RNA XLOC_004122 in bronchoalveolar lavage fluid of patients with pulmonary tuberculosis (TB),and its diagnostic value for TB.Methods A total of 45 bronchoalveolar lavage fluid samples collected from the 309th Hospital of Chinese PLA from October 2014 to March 2015 were divided into XLOC_004122 high group and XLOC_004122 low group according to the results of real-time quantitative PCR,and the clinical outcomes were compared between the two groups.Results Sputum culture conversion rate was significant higher in XLOC_004122 low group comparing with XLOC_004122 high group (at 3 weeks after treatment,75.00％ vs 39.00％,P ＜ 0.05).Meanwhile,colony forming units count in sputum culture was significant lower in XLOC_004122 low group than that in XLOC_004122 high group (at 3 weeks after treatment,0.78 ± 0.03 vs 1.33 ± 0.05,P ＜ 0.05).Conclusion These findings indicate that XLOC_004122 can be used as a prognosis predictor for pulmonary tuberculosis.关键词
长链非编码RNA/支气管肺泡灌洗液/结核病/预后Key words
long noncoding RNA/bronchoalveolar lavage fluid/tuberculosis/prognosis分类
医药卫生引用本文复制引用
蒋滢,王迪,唐倩,雷红,董跃明,刘昕..长链非编码RNA XLOC_004122对肺结核预后的辅助诊断价值[J].解放军医学院学报,2017,38(12):1106-1108,3.基金项目
部委级资助项目 （）
解放军第309医院院立课题(2014MS-002) （2014MS-002）
