解放军医学院学报2017,Vol.38Issue(12):1114-1117,1126,5.DOI:10.3969/j.issn.2095-5227.2017.12.006
40例分化型甲状腺癌术后骨转移时间的影响因素分析
Influencing factors of time from thyroidectomy to bone metastasis for differentiated thyroid carcinoma
徐倪侦 1田文 1费阳2
作者信息
- 1. 解放军总医院 普通外科,北京 100853
- 2. 解放军总医院第一附属医院 普通外科,北京 100048
- 折叠
摘要
Abstract
Objective To investigate the factors which influence the time from thyroidectomy to bone metastasis for differentiated thyroid carcinoma (DTC).Methods Forty patients treated in Chinese PLA General Hospital from January 2008 to June 2016 and diagnosed with bone metastases resulting from DTC were enrolled in our study.The factors which influenced the time from thyroidectomy to bone metastasis for DTC were analyzed by Wilcoxon test,life table analysis and Cox regression analysis.Results The time from thyroidectomy to bone metastasis for DTC was 6.6 ± 1.1 (0.5-28) years.Univariable analysis revealed that patients with extrathyroid extension (P=0.033) and multifocal lesions (P=0.012) had shorter time to metastasis.Multivariable Cox analysis revealed that extrathyroid extension (HR=2.138,P=0.033) and multifocal lesions (HR=2.293,P=0.018) influenced the metastasis.Conclusion Extrathyroid extension and multifocal lesions are the independent factors that influence the time from thyroidectomy to bone metastasis for DTC.关键词
甲状腺癌/骨转移/时间/危险因素Key words
thyroid carcinoma/bone metastasis/time/influencing factors分类
医药卫生引用本文复制引用
徐倪侦,田文,费阳..40例分化型甲状腺癌术后骨转移时间的影响因素分析[J].解放军医学院学报,2017,38(12):1114-1117,1126,5.