检验医学与临床2018，Vol.15Issue(5)：589-591,595,4.DOI:10.3969/j.issn.1672-9455.2018.05.005
模拟手机电磁辐射系统对SD大鼠耳蜗边缘细胞影响的研究
The effects of mobile phone electromagnetic radiation system on cochlea marginal cells of the SD rats
摘要
Abstract
Objective To investigate the influence of 1 800 M Hz mobile phone electromagnetic radiation system on the DNA damage,cell apoptosis and the possible mechanism of the biological effects in the SD rat cochlea marginal cells.Methods Mobile phone radiation intensity set 2 w/kg and 4 w/kg and the exposure mode was on 5 minutes off 10 minutes.Radiation time was 24 h short-term exposure type.After exposure, comet assay test,flow cytometry technology and fluorescent probe were used to detect cell DNA damage,cell apoptosis and reactive oxygen species(ROS)generation.Results T he cell phone electromagnetic radiation did not cause marginal cell DNA damage,and the rate of cell apoptosis did not increase(P>0.05).The production of ROS in 4 w/kg exposure group was significantly higher than the control group(P<0.05).Conclusion En-ergy of mobile phone does not cause cell DNA damage and cell apoptosis in the short-term exposure type in our study,but the cumulative effect of mobile phone radiation still needs to be further confirmed.Activating the ROS system is the main mechanism of electromagnetic radiation biological effects.关键词
DNA损伤/细胞凋亡/活性氧/手机电磁辐射/耳蜗边缘细胞Key words
DAN damage/cell apoptosis/reactive oxygen species/mobile telephone/electromag-netic radiation/cochlea marginal cells分类
医药卫生引用本文复制引用
张应龙,左汶奇..模拟手机电磁辐射系统对SD大鼠耳蜗边缘细胞影响的研究[J].检验医学与临床,2018,15(5):589-591,595,4.基金项目
重庆市教委科学技术研究项目(KJ1400226). （KJ1400226）
