摘要
Abstract
Objective To investigate the clinical significances of coagulation indexes and inflammatory in-dexes in patients with rheumatoid arthritis(RA)complicated with coronary heart disease(CHD).Methods In this study,patients were collected from the sixth affiliated hospital of Kunming Medical University from January 2015 to December 2016.According to different types of diseases,patients were divided into RA com-plicated with CHD group,simple RA group,simple CHD group and healthy control group,each group had 120 cases.The changes of RF,ACCP,IL-6,PT,APTT,FIB,TT,D-D,FDP,AT Ⅲ in the four groups were ana-lyzed.Results RF,ACCP and IL-6 in patients with RA complicated with CHD were significantly higher than that in other three groups(P<0.012 5).Differences of RF,ACCP and IL-6 in the simple RA group and the other three groups were statistically significant(P<0.012 5).Differences of RF and ACCP between the simple CHD group and the other three groups were statistically significant(P<0.012 5).D-D,FIB and FDP in simple RA group and RA complicated with CHD group had statistical difference with the other three groups(P<0.012 5).D-D and FDP in simple CHD group had statistical significances with simple RA group and RA com-plicated with CHD group(P<0.012 5).Conclusion D-D,FIB,FDP,ACCP and IL-6 in patients with RA com-plicated with CHD could reflect the course development and the imbalance of coagulation-fibrinolytic system, w hich could be used in clinic.关键词
类风湿关节炎/冠心病/D-二聚体/炎性指标/凝血功能Key words
rheumatoid arthritis/coronary heart disease/D-dimer/inflammatory indexes/coagula-tion function分类
医药卫生
