检验医学与临床2018，Vol.15Issue(5)：617-619,622,4.DOI:10.3969/j.issn.1672-9455.2018.05.013
PCT及CRP联合检测在新生儿感染性疾病诊断中的价值
Value of combined detection of PCT and CRP in diagnosis of neonatal infectious diseases
陈霆 1燕旭东 1涂惠英 1丁璐 1吴本清1
作者信息
- 1. 暨南大学附属第二临床医学院/深圳市人民医院新生儿科,广东深圳518020
- 折叠
摘要
Abstract
Objective To investigate the effect of procalcitonin(PCT)and C reactive protein(CRP)in the diagnosis of neonatal infectious diseases.Methods From January 2012 to December 2016,75 neonates with in-fectious diseases were treated in our hospital,among them 34 children with severe infection(severe infection group),41 cases children with local infection(local infection group),at the same time,40 children with non-in-fectious diseases were selected as control group(non-infection group),and the levels of serum PCT and CRP in each group were detected.Results PCT and CRP of severe infection group were significantly higher than that of local infection group and non-infection group(P<0.017).PCT and CRP of local infection group were significantly higher than that of non-infection group(P<0.017).The PCT and CRP in severe infection group and local infection group after treatment were lower than those before treatment(P<0.05).The CRP of se-vere infection group after treatment was significantly higher than that of local infection group(P< 0.05). When the cut-off value of PCT was 1.37 g/L,the diagnostic sensitivity and specificity were 78.70% and 100.00%.When the cut-off value of CRP was 7.79 mg/L,the diagnostic sensitivity and specificity were 90.70% and 97.50%.The sensitivity and specificity of PCT and CRP in the combined diagnosis of neonatal in-fectious diseases were 94.67% and 97.50%.Conclusion The combined detection of PCT and CRP has good diagnostic value in the diagnosis of neonatal infectious diseases,which is worthy of clinical use.关键词
降钙素原/C反应蛋白/新生儿/感染性疾病Key words
procalcitonin/C reactive protein/new born/infectious disease分类
医药卫生引用本文复制引用
陈霆,燕旭东,涂惠英,丁璐,吴本清..PCT及CRP联合检测在新生儿感染性疾病诊断中的价值[J].检验医学与临床,2018,15(5):617-619,622,4.
