摘要
Abstract
Objective To evaluate the effect of bi-level airway pressure treatment(BiPAP)on heart,lung function and blood gas indexes in patients with overlap syndrome(OS)as well as its influence on prognosis,so as to provide the basis for clinical treatment.Methods A total of 72 cases with OS were selected in Inner Mongolia medical university affiliated hospital from September 2014 to August 2016.Patients included in the study were conducted a single-center randomized controlled trial,and according to random number table,all the cases were divided into experimental group and control group,36 cases in each group.Both groups accepted a basic treatment,and the control group treated with continuous positive airway pressure(CPAP)treatment, while the treatment group treated with BiPAP treatment.Two groups treated with continuous 3 d and after treatment,on cardiopulmonary function and blood gas indexes of two groups were evaluated.At the same time,quality of life questionnaire and MRC were applied to compare between two groups so as to evaluate the short-term prognosis.Results After treatment,trial forced vital capacity(FVC),percentage of forced expira-tory volume in one second(FEV1%),percentage of maximum ventilation(M VV%)and FEV1/FVC% level were significantly higher than the control group(P<0.05).HR and RR were significantly lower than the con-trol group(P<0.05).Except the SpO2,other parameter values,such as pH,PaO2,PaCO2of treatment group were better than control group(P<0.05).Quality of life and the MRC scores of treatment group were signifi-cantly lower than that of the control group(P<0.05).Conclusion Compared with CPAP ventilation way,Bi-PAP is more conducive to the recovery of patients with OS and is helpful to cardiopulmonary function and blood gas indexes,w hich provid guarantee to improve the prognosis.关键词
重叠综合征/双水平气道正压通气/心肺功能/血气分析Key words
overlap syndrome/bi-level airway pressure ventilation/cardiopulmonary function/blood gas analysis分类
医药卫生