检验医学与临床2018，Vol.15Issue(5)：642-644,3.DOI:10.3969/j.issn.1672-9455.2018.05.021
糖尿病伴冠心病患者HPA水平与血脂、血糖等指标的相关性
Correlation of HPA levels with blood lipid and blood glucose in patients with coronary heart disease and diabetes mellitus
马国库 1高雅楠 1赵丽娜 1沈悦1
作者信息
- 1. 河北省廊坊市中医医院内分泌科 065000
- 折叠
摘要
Abstract
Objective To analyze the changes of HPA levels in patients with coronary heart disease and di-abetes mellitus,and its correlation with blood lipid and blood glucose.Methods A total of 35 patients with di-abetes mellitus(diabetes mellitus group),35 patients with coronary heart disease(CHD group),35 patients with diabetes mellitus and coronary heart disease(diabetes mellitus and coronary heart disease group)and 35 healthy subjects(health group)in the same period were selected,which were treated in the hospital from Sep-tember 2015 to September 2016.For them,serum heparanase(HPA)levels,blood pressure,blood lipids,blood glucose and other indicators were measured.Results Differences of the serum HPA levels of the patients in four groups were statistically significantly higher(P<0.05).The serum systolic pressure(SBP),fasting blood-glucose(FBG)and fasting insulin(FINS)levels of the patients in diabetes mellitus and coronary heart disease group were significantly higher than the other three groups(P<0.012 5),while the serum high density lipo-protein(HDL-C)level of the patients in diabetes mellitus and coronary heart disease group were significantly lower than the other three groups(P<0.012 5).Pearson correlation analysis showed that there were positive correlations between serum HPA level and SBP,FBG,FINS level(P<0.05),and there was a negative correla-tion with HDL-C level(P<0.05).Conclusion The serum HPA levels of patients with diabetes mellitus com-bined with coronary heart disease are increased,which could be treated as the indicator for the prediction of di-abetic patients with coronary heart disease.关键词
糖尿病/冠心病/乙酰肝素酶/血脂/血糖Key words
diabetes mellitus/coronary heart disease/heparanase/blood lipids/blood sugar分类
医药卫生引用本文复制引用
马国库,高雅楠,赵丽娜,沈悦..糖尿病伴冠心病患者HPA水平与血脂、血糖等指标的相关性[J].检验医学与临床,2018,15(5):642-644,3.
