检验医学与临床2018,Vol.15Issue(5):648-650,3.DOI:10.3969/j.issn.1672-9455.2018.05.023
mir-23a-3p及CXCL12在艾滋病患者血清中的表达水平及临床意义
Expression of mir-23a-3p and CXCL12 in serum of patients with AIDS and its clinical significance
黄富强1
作者信息
- 1. 湖北省丹江口市第一医院检验科 442700
- 折叠
摘要
Abstract
Objective To investigate the expression of mir-23a-3p and CXCL12 in the serum of AIDS pa-tients and its clinical significance.Methods A total of 70 cases of AIDS patients admitted in our hospital from January 2015 to December 2016 were selected as the study group.And 70 healthy subjects were selected as the control group.The expression of mir-23a-3p and CXCL12 in the serum of the two groups was compared.Re-sults The rate of mir-23a-3p overexpression was significantly higher in the study group than in the control group(P<0.05).At the same time,the rate of CXCL12 overexpression was significantly higher in the study group than in the control group(P< 0.05).Conclusion The overexpression of mir-23a-3p and CXCL12 is prevalent in the serum of AIDS patients.It can be regarded as an important index of disease diagnosis and prognosis evaluation,w hich needs attention from medical staff.关键词
mir-23a-3p/CXCL12/艾滋病/基因检测Key words
mir-23a-3p/CXCL12/acquired immune deficiency syndrome/gene detection分类
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黄富强..mir-23a-3p及CXCL12在艾滋病患者血清中的表达水平及临床意义[J].检验医学与临床,2018,15(5):648-650,3.