临床肝胆病杂志2018，Vol.34Issue(2)：419-423,5.DOI:10.3969/j.issn.1001-5256.2018.02.045
富含半胱氨酸的酸性分泌蛋白与原发性肝癌发生发展的关系
Research advances in secreted protein acidic and rich in cysteine in hepatocellular carcinoma
摘要
Abstract
Primary liver cancer is a common malignant tumor in clinical practice,and secreted protein acidic and rich in cysteine (SPARC) plays a very important role in the progression and metastasis of liver cancer.This article introduces the structure and biological function of SPARC and analyzes its mechanism of action in malignant tumors and its association with the progression and metastasis of liver cancer,as well as the perspectives of its application in the diagnosis and treatment of liver cancer.关键词
肝肿瘤/胞间信号肽类和蛋白质类/肿瘤转移/综述Key words
liver neoplasms/intercellular signaling peptides and proteins/neoplasm metastasis/review分类
医药卫生引用本文复制引用
冯颖,杨雪,王宪波..富含半胱氨酸的酸性分泌蛋白与原发性肝癌发生发展的关系[J].临床肝胆病杂志,2018,34(2):419-423,5.基金项目
北京市自然科学基金青年基金项目(7184219) （7184219）
北京市医院管理局临床医学发展专项经费资助(ZYLX201707) （ZYLX201707）
北京市医院管理局青年人才培养“青苗”计划基金资助(QML20151702) （QML20151702）
