摘要
Abstract
The development and progression of hepatocellular carcinoma (HCC) is associated with estrogen,which exerts its physiological effect by binding to estrogen receptor (ER).The function of ER is regulated by related genes,while the expression and function of these genes are affected by gene polymorphisms,and the genetic susceptibility to tumors is due to the combined effect of different genes and polymorphisms.Therefore,it is believed that ER gene polymorphisms may affect the development,progression,and prognosis of HCC.This article reviews the research advances in ER gene polymorphisms in recent years.关键词
癌,肝细胞/受体,雌激素/多态性,单核苷酸/综述Key words
carcinoma, hepatocellular/receptors, estrogen/polymorphism, single nucleotide/review分类
医药卫生
