摘要
Abstract
Objective To investigate the effect of combined spinal-epidural anesthesia and iliac fascial block on the nerve block effect and cognitive function in elderly patients with hip arthroplasty. Methods The 80 cases of patients undergone hip joint surgery were randomly divided into observation group and control group,40 cases in each group. The control group underwent combined spinal-epidural anesthesia,the observation group was given iliac fascia block intervention on the base of the control group, apathetic disappearance method was used to evaluate the fascia iliaca compartment block effect. The total fentanyl dosage was recorded,VAS was used to evaluate the patients pain situa-tion at every period,mini-mental state examination(MMSE) score was used to evaluate the cognitive function of pa-tients,enzyme linked immunosorbent assay method was used to detect the plasma IL-6, Sββ100,Aβ1~40levels. Re-sults The fentanyl dosage in the observation group was significantly lower than that in the control group(P<0.05). At lateral position and 6 h,1 d,2 d postoperation,the VAS of the observation group were significantly lower than those in the control group (P<0.05). In the observation group, there was statistically significant difference for the pa-tients′nerve block effect between 20 min after nerve block, lateral position and before nerve block (P<0.05);the MMSE scores of the observation group were significantly lower than those of the control group at 1 d, 2 d and 3 d postoperation (P<0.05). IL-6 levels of the two groups significantly increased at different time points (P<0.05), and which of the control group were significantly higher than observation group(P<0.05).At postoperative 6 h,1 d, two groups patients of Sββ100,Aβ1~40were significantly higher than those of preoperative levels(P<0.05),and the observation were significantly lower than the control group(P<0.05). Conclusions Combined spinal-epidural an-esthesia and iliac fascia block can effectively improve the nerve block effect and cognitive function in elderly patients with hip joint operation.关键词
腰硬联合麻醉/髂筋膜阻滞/髋关节手术/认知功能Key words
combined spinal-epidural anesthesia/iliac fascia block/hip joint surgery/cognitive function分类
医药卫生
