临床骨科杂志2018，Vol.21Issue(1)：59-61,3.DOI:10.3969/j.issn.1008-0287.2018.01.023
关节腔内注射及静脉滴注氨甲环酸对全膝关节置换术后失血的影响
Effect of tranexamic acid through intra-articular injection and intravenous drip on postoperative blood lost in primary total knee arthroplasty patients
摘要
Abstract
Objective To compare the effect of tranexamic acid through intra-articular and intravenous on postopera-tive blood lost in primary total knee arthroplasty. Methods The 100 patients who received primary total knee arthro-plasty were divided into two different groups according to random number table;50 cases in each group;and received intra-articular injection or intravenous drip tranexamic acid. General postoperative blood loss, intraoperative blood loss,obvious blood loss,postoperative 3 d of RBC,HGB,HCT levels change,blood transfusion volume and compli-cation were compared between two groups. Results There were no statistically significant differences on operation time,tourniquet time,intraoperative blood loss,postoperative drainage,general postoperative blood loss and postoper-ative 3 d of RBC,HGB,HCT levels(P>0.05). There were no statistically significant differences in blood transfu-sion volume and complications(P>0.05). Conclusions Applying intra-articular injection tranexamic acid is as ef-fective as intravenous drip tranexamic acid,which doesn′t increase blood transfusion volume and complication in pri-mary total knee arthroplasty. Intra-articular injection tranexamic acid is much more safe and convenient theoretically.关键词
全膝关节置换/氨甲环酸/关节腔注射/静脉滴注/失血Key words
total knee arthroplasty/tranexamic acid/intra-articular injection/intravenous drip/blood lost分类
医药卫生引用本文复制引用
高智慧,张帅,郭浩辉,庞龙,金群华..关节腔内注射及静脉滴注氨甲环酸对全膝关节置换术后失血的影响[J].临床骨科杂志,2018,21(1):59-61,3.基金项目
宁夏医科大学科学研究基金资助项目(编号:XZ2017012) （编号:XZ2017012）
宁夏回族自治区卫生计生委重点研究课题(编号:2017-NW-005) （编号:2017-NW-005）
