兽类学报2017，Vol.37Issue(3)：277-283,7.DOI:10.16829/j.slxb.201703008
卡麦角林对雄性黄毛鼠社会行为的影响
The effects of cabergoline on social behavior in male Rattus losea
摘要
Abstract
Fertility control reduces the birth rate of rodent populations and influences animal reproductive capability.By contrast,the effects of sterilants on individual behaviors may affect the social hierarchy of populations,and interfere with reproduction in normal animals.To understand the effects of cabergoline treatment dosage and treatment duration on the behavior of male Rattus losea,40 male rats were randomly divided into five groups and treated with 0,50,and 100 μg/kg cabergoline for 3 consecutive days.One male subject from the pre-treatment group (T750,T7100) was assigned to dyadic encounters with one subject from the control group (C) on the first day after the end of the three-day treatment.T2450 and T24100 rats encountered the same rat from C on the 18th day after the end of the three-day treatment.T750and T7100 were assigned to dyadic encounters with normal females on the fourth day after the end of the three-day treatment.T2450 and T24100 rats encountered normal females on the 21st day after the end of the three-day treatment.Social behaviors between the same sex and the opposite sex were observed for 30 min and videotaped.The results showed that cabergoline treatment negatively affected the investigative and aggressive behavior of male R.losea,and reduced the aggression duration and frequency of males toward females.The frequency of investigation,grooming and resting in males that encountered female counterparts were significantly different between pre-and post-treatment with 100 μμg/kg cabergoline.In conclusion,cabergoline treatment disturbs the inter-or intra-sexual social behaviors of R.losea.Furthermore,with longer duration post-treatment,the behavioral data in our experiment were not significantly different compared with pre-treatment.These results indicate that the effects of drug on social behavior of the male can gradually disappear after suspending cabergoline treatment.关键词
黄毛鼠/卡麦角林/不育控制/社会行为Key words
Cabergoline/Fertility control/Rattus losea/Social behavior分类
生物科学引用本文复制引用
秦姣,苏欠欠,刘全生..卡麦角林对雄性黄毛鼠社会行为的影响[J].兽类学报,2017,37(3):277-283,7.基金项目
国家自然科学基金项目(31301684) （31301684）
广东省自然科学基金项目(2015A030313860) （2015A030313860）
广东省科技计划项目(2013B050800024,2015A020209092,2016A020210054) （2013B050800024,2015A020209092,2016A020210054）
