现代妇产科进展2018，Vol.27Issue(3)：195-197,3.DOI:10.13283/j.cnki.xdfckjz.2018.03.009
炔雌醇环丙孕酮片对PCOS患者血清抗苗勒氏管激素的影响
The impact of ethinylestradiol cyproterone on serum anti-Müllerian hormone levels in women with polycystic ovarian syndrome
摘要
Abstract
Objective:To observe the impact of ethinylestradiol cyproterone on serum anti-Müllerian hormone levels in women with polycystic ovarian syndrome. Methods:Women with PCOS of age 20 to 30 who attended to outpatient department of Gynecology of Shanghai Sixth People's Hospital East Campus from January 2015 to June 2017 were enrolled. After in-formed consents were signed, patients were prescribed with ethinylestradiol cyproterone for 3 months. Endocrine and metabolic parameters were compared before and after treatment. Age and BMI matched healthy women were recruited as control. Results:Fifty from 63 patients comple-ted the study. Serum AMH was significant increased in PCOS than control group before treat-ment[(10. 87±4. 47)ng/ml vs (8. 35±4. 25)ng/ml,P<0. 05],but no difference were found between normal weight and overweight/obese patients. Serum AMH was significantly decreased after 3 month of treatment[(10. 85±3. 98)ng/ml vs (8. 22±3. 03)ng/ml,P=0. 000]. Conclu-sion:Serum AMH levels were significantly decreased after short-term treatment with ethi-nylestradiol cyproterone.关键词
多囊卵巢综合征/抗苗勒氏管激素/炔雌醇环丙孕酮片Key words
Polycystic ovarian syndrome/Anti-Müllerian hormone/Ethinylestradiol cyproterone分类
医药卫生引用本文复制引用
熊苗,朱洁萍,朱海润,罗艳群,陆继红,王军,黄红玲,李莉,刘阳,陈宇..炔雌醇环丙孕酮片对PCOS患者血清抗苗勒氏管激素的影响[J].现代妇产科进展,2018,27(3):195-197,3.基金项目
上海市浦东新区卫计委联合攻关项目的资助(No:PW2013D-6) （No:PW2013D-6）
