中国全科医学2018，Vol.21Issue(4)：486-490,5.DOI:10.3969/j.issn.1007-9572.2018.04.024
艾滋病合并肝硬化腹腔积液的名老中医用药规律研究
Regularities of Prescribing Therapy for AIDS Combined with Ascites Due to Cirrhosis by an Elderly Famous TCM Doctor Named LI Fa-zhi
摘要
Abstract
Objective To investigate the regularities of prescribing therapy for AIDS combined with ascites due to cirrhosis by LI Fa-zhi, an aged famous TCM doctor. Methods According to the inclusion and exclusion criteria, from Elderly Famous TCM Doctors'Clinical Diagnosis and Treatment Data Collection System, we selected 259 cases of AIDS combined with ascites due to cirrhosis treated by professor LI Fa-zhi from October 2007 to September 2014 and finally enrolled 240 cases (totaled 794 visits) after excluding 19 cases without response. Complex Network Analysis System for Clinical TCM-treated Cases (Liquorice software) was used for descriptive statistical analysis and complex network analysis. Results For AIDS combined with ascites due to cirrhosis treated by LI Fa-zhi , the three drugs used most frequently were Atractylodes (770 times), Astragalus membranaceus (761 times) and Alisma (707 times); the three combinations used most commonly were Atractylodes-Astragalus membranaceus (747 times), Poria cocos-Alisma (698 times) and Angelica-Alisma (696 times); the core drugs used for invigorating qi and spleen and promoting dieresis, for activating blood circulation, for astringing liver, soothing liver and promoting the circulation of qi, for inducing diuresis to reduce edema, were Atractylodes, Astragalus membranaceus and Poria cocos, Angelica and Ligusticum wallichii, White peony root, Bupleurum, and Folia perillae acutae, Alisma, Radix stephaniae tetrandrae, Fructus chaenomelis lagenariae, Pericarpium arecae, Indian bread exodermis and Epicarpium benincasae, respectively; the core prescriptions were Dangguishaoyao powder with Fangjihuangqi decoction, Modified Jiming powder, respectively. Conclusion LI Fa-zhi treats this disease mainly by soothing liver, invigorating the spleen, regulating qi, inducing diuresis for removing edema , as well as removing blood stasis, nourishing qi and eradicating qi stagnation.关键词
获得性免疫缺陷综合征/肝硬化腹腔积液/李发枝/复杂网络分析/中药疗法Key words
Acquired immunodeficiency syndrome/Ascites due to cirrhosis/LI Fa-zhi/Complex network analysis/TCM therapy分类
医药卫生引用本文复制引用
王丹妮,陈莉华,吴瑞红,许前磊,张晓伟,张丽,孙苗娜,邬欣怡,郭会军..艾滋病合并肝硬化腹腔积液的名老中医用药规律研究[J].中国全科医学,2018,21(4):486-490,5.基金项目
国家科技重大专项(2012ZX10005010-001-002) （2012ZX10005010-001-002）
国家自然科学基金资助项目(81102575) （81102575）
国家中医药管理局基地专项(JDZX2015164) （JDZX2015164）
河南省特色学科中医学学科建设项目(STS-ZYX-2017017) （STS-ZYX-2017017）
2015年河南中医学院中医药与经济社会发展研究中心科研项目(2015JDYB15) （2015JDYB15）
2016年河南中医学院科技创新人才项目(2016XCXRC03) （2016XCXRC03）
