中国全科医学2018，Vol.21Issue(6)：643-647,5.DOI:10.3969/j.issn.1007-9572.2017.00.193
基于健康调查量表的脑卒中患者报告结局与临床客观指标的相关性研究
Association Analysis on Clinical Objective Indicators and Patient-reported Outcomes in Patients with Stroke based on the SF-36 Scale
摘要
Abstract
Objective To explore the relationship between patient-reported outcomes (PRO) and clinical objective indicators in stroke patients. Methods One hundred inpatients diagnosed with stroke and received treatment in Department of Neurology, First Affiliated Hospital of Kunming Medical University from May 2010 to March 2011 were selected as the subjects, and SF-36 Scale was used to measure their PRO. The clinical objective indicators measured on the second day after admission were collected from the medical records, including albumin, globulin, urea, fasting blood glucose, blood potassium, platelet count, activated partial thromboplastin time, and degree of education. The correlation between PRO and clinical objective indicators was analyzed by simple correlation and canonical correlation. Results Simple correlation analysis showed that globulin was negatively correlated with bodily pain (BP) , vitality (VT) (P<0.05) ; urea was negatively correlated with physical functioning (PF) (P<0.05) ; fasting blood glucose was negatively correlated with general health perceptions (GH) (P<0.05) ; blood potassium was negatively correlated with PF (P<0.05) ; platelet count was negatively correlated with PF (P<0.05) ; educational level was positively correlated with PF,BP, VT, and emotional role functioning (RE) (P<0.05) . Canonical correlation analysis showed that canonical variables (μ1, ν1), (μ2, ν2) existed correlation (r=0.536 0, r=0.325 6, P<0.05) . Canonical variable coefficient of globulin and μ1was -0.832 2, canonical variable coefficient of activated partial thromboplastin time and μ1was 0.358 5;canonical variable coefficient of platelet count and μ2was 0.581 6, canonical variable coefficient of educational level and μ2was 0.672 0; canonical variable coefficient of VT and ν1was 1.061 7, canonical variable coefficient of mental health (MH) and ν1 was -0.761 8, canonical variable coefficient of PF and ν2was -0.950 1, canonical variable coefficient of GH and ν2was 0.443 8. Globulin was highly negatively correlated with μ1(r=-0.835 0, P<0.05). PF was highly negatively correlated with ν2(r=-0.738 6, P<0.05) . VT was highly positively correlated with ν1(r=0.727 2, P<0.05) . Conclusion Clinical objective indicators correlate with PROs in stroke patients. Therefore, taking interventions based on the values of these indicators is of some significance in improving the PROs of these patients.关键词
卒中/患者报告结局/临床客观指标/关联性分析Key words
Stroke/Patient-reported outcomes/Clinical objective indicators/Correlation analysis分类
医药卫生引用本文复制引用
许清安,常履华,万崇华,孙凤琴,许传志,刘洲..基于健康调查量表的脑卒中患者报告结局与临床客观指标的相关性研究[J].中国全科医学,2018,21(6):643-647,5.基金项目
国家自然科学基金资助项目(71373058,81460519) （71373058,81460519）
广东省科技计划项目(2013B021800074) （2013B021800074）
