中国输血杂志2017，Vol.30Issue(12)：1374-1376,3.DOI:10.13303/j.cjbt.issn.1004-549x.2017.12.017
某院新疆地区的维吾尔族、哈萨克族人群Kell血型基因频率调查
Investigation of the Kell blood group gene frequency in one hospital of Uygur and Kazak population in Xinjiang,China
陈伟 1李菲 1文军 1兰炯采2
作者信息
- 1. 新疆维吾尔自治区人民医院输血科,新疆乌鲁木齐830001
- 2. 南方医科大学南方医院
- 折叠
摘要
Abstract
Objective To investigate the gene frequency of Kell blood group in one hospital of Xinjiang Uygur and Kazak population,and to evaluate the risks of adverse transfusion reactions,especially in pregnancy.Methods The K and k antigens of the Kell blood system on the surface of erythrocytes were detected with monoclonal serum.The screening were performed using direct saline media centrifugationand the Coombs' test.Results A total of 914 blood cases were analyzed including 757 Uygur individuals and 157 Kazak individuals.The Uygur population presented 742 cases of the Kel (1-2+) phenotype and 15 cases of Kel the (1+2+) phenotype while no Kel (1+2-) phenotype was not detected.The Kazak,on the other hand,presented 153 cases of the Kel (1-2+) phenotype and 4 cases of the Kel (1+2+) phenotype while the Kel (1+2-) phenotype was not found either.In the Uygur population,the frequencies of the K and the k gene were 0.009 9 vs 0.990 1.In the Kazak population,the frequencies of the K and the k gene were 0.012 7 vs 0.987 3.Conclusion The frequencies of the K gene in Xinjiang Uygur and Kazak population differs and each group possesses its own characteristics.关键词
维吾尔族/哈萨克族/Kell血型/基因频率Key words
Uygur/Kazak/Kell blood type/gene frequency分类
临床医学引用本文复制引用
陈伟,李菲,文军,兰炯采..某院新疆地区的维吾尔族、哈萨克族人群Kell血型基因频率调查[J].中国输血杂志,2017,30(12):1374-1376,3.
