中国医科大学学报2017，Vol.46Issue(12)：1076-1081,6.DOI:10.12007/j.issn.0258-4646.2017.12.005
40周岁及以上双胎妊娠产妇的临床结局分析
Clinical Outcome Analysis of Twin Pregnancies in Women Over the Age of 40 Years
摘要
Abstract
Objective To examine perinatal complications and outcomes of twin pregnancies in women aged over 40 years.Methods A retrospective study was performed on the clinical data of 3 127 twin pregnancies,managed in 12 national hospitals from January2013-December 2013,to analyze differences in perinatal complications and outcomes between women aged over 40 years,and those aged 35 to ＜40 years and 18 to ＜35 years.Results For twin pregnancies,the incidence of postpartum hemorrhage,abortion,early preterm birth,termination of gestation,very low birth weight infants,mild neonatal asphyxia,and preterm births in women aged over 0 years was significantly higher than in women aged 35 to ＜40 years and 18 to ＜35 years (P ＜ 0.05).Among women aged over 40 years and those aged 35 to ＜40 years,the incidence of gestational hypertension was not significantly higher than in women aged 18 to ＜35 years for twin pregnancies (P ＞ 0.05).Conclusion Women aged over 40 years with twin pregnancies were more likely to develop maternal complications and poor perinatal outcomes.Therefore,twin pregnancies in women aged over 40 years should receive comprehensive perinatal management to extend the gestation and improve the perinatal prognosis.关键词
双胎妊娠/高龄产妇/辅助生殖/产后出血/新生儿窒息Key words
twin pregnancy/advanced maternal age women/assisted reproductive technology/postpartum hemorrhage/neonatal asphyxia分类
医药卫生引用本文复制引用
李洋洋,那全,刘彩霞,尹少尉..40周岁及以上双胎妊娠产妇的临床结局分析[J].中国医科大学学报,2017,46(12):1076-1081,6.基金项目
国家卫生计生委公益性行业科研专项(201402006) （201402006）
辽宁省产科疾病转化医学研究中心及协同研究网络建设(2014225007) （2014225007）
