中国中西医结合外科杂志2017，Vol.23Issue(6)：587-590,4.DOI:10.3969/j.issn.1007-6948.2017.06.002
肝细胞癌微血管侵犯与术后复发及预后的相关性
Correlation of Microvascular Invasion with Recurrence and Prognosis of Patients with Hepatocellular Carcinoma after Liver Resections
胡伟 1马新 2袁亮3
作者信息
- 1. 四川省泸州市中医医院外科,泸州646000
- 2. 西南医科大学第二附属医院普外科,泸州646099
- 3. 四川省泸州市第七人民医院外科,泸州646000
- 折叠
摘要
Abstract
Objective To investigate microvascular invasion and its effect on the recurrence and prognosis of patients with hepatocellular carcinoma (HCC) after liver resections.Methods The clinical data and pathological features of liver cancer patients (149 cases) with radical resection were retrospectively analyzed.The patients were divided into two groups:experimental group (94 cases,with microvascular invasion) and control group (55 cases,without microvascular invasion).The tumor free survival time was recorded and recorded.The related factors of microvascular invasion were analyzed by logistic regression,and the risk factors for early postoperative recurrence (within 2 years after surgery) were predicted by Cox regression.The ROC curve was used to calculate and evaluate the microvascular invasion and related factors of early postoperative recurrence.Results Logistic regression analysis showed that tumor diameter was the independent predictor of microvascular invasion in HCC (OR =7.439,95％CI =1.478-36.423).The area under ROC curve was 0.843.The larger the tumor diameter was,the greater the probability of microvascular invasion was (P ＜ 0.001).Cox regression analysis showed that gross tumor type and microvascular invasion were independent predictors of early recurrence in patients with HCC after operation (within 2 years).The areas under ROC curve were 0.689 and 0.732,respectively.Patients with higher gross tumor grade or with microvascular invasion were more likely to relapse early (P ＜ 0.001).Conclusion Patients with HCC with bigger tumor size are more likely to have microvascular invasion.The more microvascular invasion and with higher grade of the tumor classifications,the more likely the tumor is to recur earlier.关键词
肝细胞癌/微血管侵犯/复发/预后Key words
Hepatocellular carcinoma/microvascular invasion/recurrence/prognosis分类
医药卫生引用本文复制引用
胡伟,马新,袁亮..肝细胞癌微血管侵犯与术后复发及预后的相关性[J].中国中西医结合外科杂志,2017,23(6):587-590,4.
