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通脉汤治疗高危人群围术期下肢深静脉血栓形成疗效分析

李灿辉 吴征杰 曾焰辉 杜雪莲 何家雄 司徒晓鹏

中国中西医结合外科杂志2017,Vol.23Issue(6):591-594,4.
中国中西医结合外科杂志2017,Vol.23Issue(6):591-594,4.DOI:10.3969/j.issn.1007-6948.2017.06.003

通脉汤治疗高危人群围术期下肢深静脉血栓形成疗效分析

Curative Effect Analysis on Tongmai Decoction on Deep Venous Thrombosis of Lower Extremity in High Risk Population

李灿辉 1吴征杰 1曾焰辉 1杜雪莲 1何家雄 1司徒晓鹏1

作者信息

  • 1. 广东省佛山中医院骨七科,佛山 528000
  • 折叠

摘要

Abstract

Objective To investigate the effect of Tongrnai Decoction on deep venous thrombosis (DVT) of lower extremity in high risk patients.Methods The patients with complication of lower extremity fractures after operation (84 cases) were randomly divided into treatment group and control group (n =42).The patients in control group were treated with low molecular weight heparin.The patients in treatment group were treated with Tongmai Decoction based on the control processing.The D-dimer (D-D) indicators and blood flow indices were compared between two groups before and after treatment.Results The total effective rates were 95.24% in the treatment group and 76.19% in the control group (P =0.013).The D-D [(221.25 ± 32.78) and (152.45 ± 25.98)ng/mL],fibrinogen [(212.22 ± 22.45) and (122.36 ± 15.23) g/L],low shear rate of whole blood viscosity [(9.86 ± 1.74) and (4.36 ± 0.85) mPa · s] and high shear rate of whole blood viscosity [(5.72 ± 1.63) and (3.63 ± 0.85) mPa.s] of treatment group on day 3 and 7 after treatment were lower than those in the control group [(278.96 ± 28.96) and (211.25 ± 21.96) ng/mL,(289.36 ± 34.63) and (228.69 ± 28.36) g/L,(12.67 ± 1.46)and (9.52 ± 0.96) mPa · s,(8.37 ± 1.72)and (6.32 ± 1.21) mPa · s].Conclusion Tongrnai Decoction can effectively improve the D-D level and antiplatelet aggregation in DVT patients and improve the therapeutic effect of DVT,which is safe and reliable.

关键词

通脉汤/低分子肝素/行气破瘀/深静脉血栓形成

Key words

Tongmai Decoction/low molecular weight heparin/activating qi to resolve blood stasis/deep vein thrombosis

分类

医药卫生

引用本文复制引用

李灿辉,吴征杰,曾焰辉,杜雪莲,何家雄,司徒晓鹏..通脉汤治疗高危人群围术期下肢深静脉血栓形成疗效分析[J].中国中西医结合外科杂志,2017,23(6):591-594,4.

基金项目

广东省佛山市科委基金项目(2014AB00323) (2014AB00323)

中国中西医结合外科杂志

OACSTPCD

1007-6948

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