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德钦乌头块根化学成分的研究

刘王艳 沈勇 何丹 郭成鑫 李桂琼 段晓燕 熊娇 陈严平

中成药2018,Vol.40Issue(2):368-374,7.
中成药2018,Vol.40Issue(2):368-374,7.DOI:10.3969/j.issn.1001-1528.2018.02.024

德钦乌头块根化学成分的研究

Chemical constituents from the roots tuber of Aconitum ouvrardianum

刘王艳 1沈勇 1何丹 1郭成鑫 1李桂琼 1段晓燕 1熊娇 1陈严平1

作者信息

  • 1. 云南农业大学,云南昆明650201
  • 折叠

摘要

Abstract

AIM To study the chemical constituents from the roots tuber of Aconitum ouvrardianum H..METHODS The ethyl acetate fraction of methy extract from A.ouvrardianum roots tuber was isolated and purified by silica,aluminium oxide column,Sephadex LH-20,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Eighteen compounds were isolated and identified as kongboendine (1),anisoezochasmaconitine (2),lipo-14-O-anisoylbikhaconine (3),franchetine (4),talatisamine (5),chasmanine (6),crassicauline A (7),chasmaconitine (8),14-dehydrotalatisamine (9),lipoindaconitine (10),indaconitine (11),yunaconitine (12),lipoyunaconitine (13),liljestrandisine (14),transconitine B (15),ouvrardiantine (16),atropurpursine (17),8-deacetylyunaconitine (18).CONCLUSION Compounds 1-4,9-10,13,15,17 are isolated from this plant for the first time.

关键词

德钦乌头/块根/化学成分/分离鉴定

Key words

Aconitum ouvrardianum H./roots tuber/chemical constituents/isolation and identification

分类

医药卫生

引用本文复制引用

刘王艳,沈勇,何丹,郭成鑫,李桂琼,段晓燕,熊娇,陈严平..德钦乌头块根化学成分的研究[J].中成药,2018,40(2):368-374,7.

基金项目

国家自然科学基金项目(21362045) (21362045)

中成药

OA北大核心CSCDCSTPCD

1001-1528

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