中成药2018,Vol.40Issue(2):375-378,4.DOI:10.3969/j.issn.1001-1528.2018.02.025
美洲大蠊化学成分的研究
Chemical constituents from Periplaneta Americana
高允 1梁柳春 1王瑞 1成亮 2郭夫江 3李医明1
作者信息
- 1. 上海中医药大学中药学院,上海201203
- 2. 浙江京新药业股份有限公司,浙江绍兴312500
- 3. 上海京新生物医药有限公司,上海201203
- 折叠
摘要
Abstract
AIM To study the chemical constituents from P.americana L..METHODS The 90% ethanol extract from P.americana was isolated and purified by silica,ODS,Sephadex LH-20,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Sixteen compounds were isolated and identified as L-leucine (1),uracil (2),acetamide (3),valine (4),γ-aminobutyric acid (5),glycerol (6),methyl,2-piperidinecarboxylate (7),pyrazine (8),protocatechuic acid-4-O-β-D-glucopyranoside (9),thymidine (10),cyclo (Pro-Ser) (11),cyclo (Pro-Asn) (12),phenylalanine (13),4-(2-aminoethyl) benzene-1,2-diol (14),inosine (15),tyramine (16).CONCLUSION Compounds 3,7-12,14,16 are all isolated from Periplaneta americana and genus Periplaneta for the first time.关键词
美洲大蠊/化学成分/分离鉴定Key words
Periplaneta Americana/chemical constituents/isolation and identification分类
医药卫生引用本文复制引用
高允,梁柳春,王瑞,成亮,郭夫江,李医明..美洲大蠊化学成分的研究[J].中成药,2018,40(2):375-378,4.