肠道上皮主要葡萄糖转运载体及其作用机制OA北大核心CSCDCSTPCD
Intestinal Epithelium Major Glucose Transporters and Their Action Mechanisms
葡萄糖在肠道的吸收主要通过Na+依赖性葡萄糖转运载体1(SGLT1)和易化葡萄糖转运载体2(GLUT2)实现.许多影响肠道葡萄糖吸收功能的因素都是通过调控SGLT1和GLUT2转录水平、mRNA稳定性及蛋白水平来实现的.通过对葡萄糖转运载体结构和功能的研究,不仅为人类肥胖症和糖尿病等相关疾病提供潜在药物靶点,还能为调节动物营养物质吸收提供思路.本文综述了肠道上皮主要葡萄糖转运载体SGLT1和GLUT2的功能和影响其在肠道上皮表达的因素,旨在从分子…查看全部>>
Glucose is primarily absorbed via sodium dependent glucose transporter 1(SGLT1)and facilitative glucose transporter 2(GLUT2)in intestinal epithelia. Many factors involved in the glucose absorption in the gut are acted by regulation of SGLT1 and GLUT2 at the transcription level, mRNA stability and protein level. Through the studies on structures and functions of those glucose transporters, not only for human relative dis-ease including obesity and diabetes to…查看全部>>
卢垚;孙佩佩;宋代军
西南大学动物科技学院,北碚400715西南大学动物科技学院,北碚400715西南大学动物科技学院,北碚400715
农业科技
葡萄糖转运载体肠道上皮Na+依赖性葡萄糖转运载体1易化葡萄糖转运载体2机制
glucosetransporterintestinal epithelialSGLT1GLUT2mechanism
《动物营养学报》 2018 (1)
50-58,9
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