动物营养学报2018，Vol.30Issue(1)：50-58,9.DOI:10.3969/j.issn.1006-267x.2018.01.008
肠道上皮主要葡萄糖转运载体及其作用机制
Intestinal Epithelium Major Glucose Transporters and Their Action Mechanisms
摘要
Abstract
Glucose is primarily absorbed via sodium dependent glucose transporter 1(SGLT1)and facilitative glucose transporter 2(GLUT2)in intestinal epithelia. Many factors involved in the glucose absorption in the gut are acted by regulation of SGLT1 and GLUT2 at the transcription level, mRNA stability and protein level. Through the studies on structures and functions of those glucose transporters, not only for human relative dis-ease including obesity and diabetes to provide potential drug target, but also can provide ideas for controlling animal nutrition absorption. This review summarized glucose transporters SGLT1 and GLU2, their functions and factors affecting their expression, and conducted to elucidate the process of glucose absorption in intestine and regulation of glucose homeostasis at the molecular level.关键词
葡萄糖/转运载体/肠道上皮/Na+依赖性葡萄糖转运载体1/易化葡萄糖转运载体2/机制Key words
glucose/transporter/intestinal epithelial/SGLT1/GLUT2/mechanism分类
农业科技引用本文复制引用
卢垚,孙佩佩,宋代军..肠道上皮主要葡萄糖转运载体及其作用机制[J].动物营养学报,2018,30(1):50-58,9.
