动物营养学报2018，Vol.30Issue(1)：66-74,9.DOI:10.3969/j.issn.1006-267x.2018.01.010
泛素-蛋白酶体途径在生殖细胞减数分裂过程中的作用及机制
Roles of Ubiquitin-Proteasome Pathway in Meiotic Division of Germ Cells and Its Mechanism
摘要
Abstract
Ubiquitin-proteasome pathway(UPP)is the main pathway of protein degradation in eukaryotic cells, and it plays a very important regulatory role in the protein interaction, protein activity, signal transduc-tion and cell cycle progression. Studies have indicated that UPP is essential for regulating meiotic homologous recombination, meiotic sex chromosome inactivation, meiotic resumption and extrusion of the first polar body in gametogenesis of human and animals. This paper summarized the signal transduction and regulation mecha-nism of UPP in the regulation of meiosis and the gametogenesis of animals in order to provide a reference for subsequent research.关键词
泛素-蛋白酶体途径/泛素化/生殖细胞/减数分裂Key words
ubiquitin-proteasome pathway/ubiquitination/germ cells/meiotic division分类
农业科技引用本文复制引用
彭馥芝,董莲花,冉茂良,翁波,陈斌..泛素-蛋白酶体途径在生殖细胞减数分裂过程中的作用及机制[J].动物营养学报,2018,30(1):66-74,9.基金项目
国家现代农业产业技术体系建设专项资金(CARS-36) （CARS-36）
