口腔疾病防治2018，Vol.26Issue(3)：195-199,5.DOI:10.12016/j.issn.2096-1456.2018.03.011
龋病相关微生物群落结构与功能的多组学研究进展
A multiomics approach to study the associations between microbial communities and functions and dental car-ies
摘要
Abstract
The pathogenic mechanisms by which oral microbial communities affect the occurrence and development of dental caries remain unclear. Applications that make use of high-through put sequencing technologies and metaomics approaches to research dental caries etiology can provide new ideas about disease prevention and treatment. In this arti-cle, we review advanced research presented in metaomics studies, including genomic, metagenomic, metatranscriptomic, metaproteomic and metabolomics studies of dental caries.关键词
龋病/口腔微生物群落/微生态/宏基因组学/宏转录组学/宏蛋白质组学/宏代谢组学Key words
Dental caries/Oral microbial community/Micro-ecology/Metagenomics/Metatranscriptomics/Metaproteomics/Metabolomics分类
医药卫生引用本文复制引用
霍媛媛,韩轩,李雨庆..龋病相关微生物群落结构与功能的多组学研究进展[J].口腔疾病防治,2018,26(3):195-199,5.基金项目
国家自然科学基金(81470035) （81470035）
