解放军医药杂志2018,Vol.30Issue(2):9-12,4.DOI:10.3969/j.issn.2095-140X.2018.02.003
细胞免疫治疗在中晚期肝癌的应用效果观察
Effect Observation of Cellular Immunotherapy in Treatment of Patients with Middle-advanced Hepatocellular Carcinoma
摘要
Abstract
Objective To observe effect of cellular immunotherapy in treatment of patients with middle-advanced hepatocellular carcinoma. Methods A total of 105 patients with middle-advanced hepatocellular carcinoma admitted during February 2016 and September were divided into observation group(n=54) and control group(n=51) according to therapeutic methods. Control group was treated with recombinant human endostatin injection combined with hepatic ar-terial chemoembolization,while observation group was added with cellular immunotherapy on the basis of treatment for control group. Effects,life quality and incidence rate of adverse reaction were observed in two groups.Results The ef-fective rate and improved condition of life quality in observation group were superior than those in control group (P <0.05). There was no significant difference in incidence rate of adverse reaction between two groups(P> 0.05). Con-clusion The application of cellular immunotherapy in treatment of patients with middle-advanced hepatocellular carcino-ma may significantly improve effective rate and life quality and reduce incidence rate of adverse reaction.关键词
肝肿瘤/免疫疗法,过继/重组人血管内皮抑制素/肝动脉栓塞化疗Key words
Liver neoplasms/Immunotherapy/adoptive/Recombinant human endostatin/Transcatheter hepatic arterial chemoembolization分类
医药卫生引用本文复制引用
武振明,史素梅,王凌凌,郭茜,王帅兵,齐秀恒..细胞免疫治疗在中晚期肝癌的应用效果观察[J].解放军医药杂志,2018,30(2):9-12,4.基金项目
河北省科学技术项目(162777134) (162777134)