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细胞免疫治疗在中晚期肝癌的应用效果观察

武振明 史素梅 王凌凌 郭茜 王帅兵 齐秀恒

解放军医药杂志2018,Vol.30Issue(2):9-12,4.
解放军医药杂志2018,Vol.30Issue(2):9-12,4.DOI:10.3969/j.issn.2095-140X.2018.02.003

细胞免疫治疗在中晚期肝癌的应用效果观察

Effect Observation of Cellular Immunotherapy in Treatment of Patients with Middle-advanced Hepatocellular Carcinoma

武振明 1史素梅 1王凌凌 1郭茜 1王帅兵 1齐秀恒1

作者信息

  • 1. 065000河北 廊坊,中国石油天然气集团公司中心医院肿瘤科
  • 折叠

摘要

Abstract

Objective To observe effect of cellular immunotherapy in treatment of patients with middle-advanced hepatocellular carcinoma. Methods A total of 105 patients with middle-advanced hepatocellular carcinoma admitted during February 2016 and September were divided into observation group(n=54) and control group(n=51) according to therapeutic methods. Control group was treated with recombinant human endostatin injection combined with hepatic ar-terial chemoembolization,while observation group was added with cellular immunotherapy on the basis of treatment for control group. Effects,life quality and incidence rate of adverse reaction were observed in two groups.Results The ef-fective rate and improved condition of life quality in observation group were superior than those in control group (P <0.05). There was no significant difference in incidence rate of adverse reaction between two groups(P> 0.05). Con-clusion The application of cellular immunotherapy in treatment of patients with middle-advanced hepatocellular carcino-ma may significantly improve effective rate and life quality and reduce incidence rate of adverse reaction.

关键词

肝肿瘤/免疫疗法,过继/重组人血管内皮抑制素/肝动脉栓塞化疗

Key words

Liver neoplasms/Immunotherapy/adoptive/Recombinant human endostatin/Transcatheter hepatic arterial chemoembolization

分类

医药卫生

引用本文复制引用

武振明,史素梅,王凌凌,郭茜,王帅兵,齐秀恒..细胞免疫治疗在中晚期肝癌的应用效果观察[J].解放军医药杂志,2018,30(2):9-12,4.

基金项目

河北省科学技术项目(162777134) (162777134)

解放军医药杂志

OACSTPCD

2095-140X

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