中国实用神经疾病杂志2018，Vol.21Issue(1)：82-85,4.DOI:10.12083/SYSJ.2018.01.021
78例椎管内神经鞘瘤临床病理学分析
Vertebral canal sehwannoma:a clinicopathological study of 78 cases
摘要
Abstract
Objective To observe the clinical and pathological features ,diagnosis and differential diagnosis of vertebral canal sehwannoma .Methods The clinical presentation ,histological observation and immunohistochemical staining were analyzed in 78 cases and related literatures were reviewed .Results The incidence ratio of vertebral canal sehwannoma in male and female were 1.4 :1 .The ages ranged from 14 to 67 years old ,with mean age of 51 .The site of occurrence included lumbar vertebra (35 cases , 44.8％ ) ,thoracic vertebra (24 cases ,30.7％ ) ,cervical vertebra (17 cases ,21.8％ ) and sacrococcygeal region (2 cases ,2.6％ ) . Histological analysis showed that the tumor was composed of spindle ,oval or fusiform cells arranged in fascicles or paliforms , hemorrhage and cystic changes were commonly observed .Immunohistochemical staining showed that the cells were typically and strongly positive for S-100 ,SOX-10 and PgP9.5 ,some cases stained for CD34 .Of the 54 of 78 cases ,the follow-up period was 3 months to 24 years ,1 case had recurrence .Conclusion Vertebral canal sehwannoma is a rare tumor with good prognosis and com-plex histological expression .Its differential diagnosis includes exothelioma ,astrocytoma and others .关键词
软组织肿瘤/椎管内/神经鞘瘤/诊断鉴别/脑脊膜瘤Key words
Soft tissue neoplasms/Vertebral canal/Sehwannoma/Differential diagnosis/Meningioma分类
医药卫生引用本文复制引用
冯怡锟,胡桂明,常佳,吴会芳,付文静,顾斌,张敏,任景丽..78例椎管内神经鞘瘤临床病理学分析[J].中国实用神经疾病杂志,2018,21(1):82-85,4.基金项目
河南省医学科技攻关计划项目(编号:201503099) （编号:201503099）
