中国实用神经疾病杂志2018，Vol.21Issue(2)：133-135,139,4.DOI:10.12083/SYSJ.2018.02.034
青年脑梗死患者发病危险因素临床分析
Analysis of risk factors in young patients with cerebral infarction
摘要
Abstract
Objective To analyze the risk factors of young cerebral infarction caused by large artery atherosclerosis (LAA) or penetrating artery disease(PAD) ,and to provide the basis for clinical application .Methods A total of 120 patients with cerebral infarction caused by LAA or PAD diagnosed in our hospital under 45 years old were selected as the study subjects ,and 120 cases non-stroke young under 45 years old in the same period were selected as a control group .We compared their clinical data including hypertension ,smoking ,sleep-disordered breathing ,fasting blood glucose (FBG) ,glycosylated hemoglobin A1c(HbA1c) ,uric acid (UA) ,total cholesterol(TG) ,low-density lipoprotein-C(LDL-C) ,high-density lipoprotein-C(HDL-C) ,triglyceride (TC) ,homo-cysteine (HCY) ,to explore the risk factors for the incidence of young cerebral infarction caused by LAA or PAD .Results Hyper-tension of the case group was significantly higher than that of the control group ,the difference was statistically significant ;The lev-el of UA in the case group was (409.56 ± 149.931 ) umol/L ,which was significantly higher than that in the control group (375.53 ± 106.184 umol/L) ,and the difference was statistically significant .The level of TC in case group was (2.325 ± 1.753) mmol/L ,which was significantly higher than that in control group (1.874 ± 1.494) mmol/L ,the difference was statistically sig-nificant .Logistic regression analysis showed that hypertension ,uric acid and triglyceride were positively correlated with the inci-dence of cerebral infarction in young patients caused by LAA and PAD (P<0.05) .Conclusion Hypertension ,uric acid and tri-glyceride are independent risk factors for the development of cerebral infarction in young patients caused by LAA and PAD .Con-trolling of young people's hypertension ,uric acid and triglyceride can reduce the incidence of such young cerebral infarction ,and has positive significance for the first-degree prevention of such young cerebral infarction .关键词
青年脑梗死/危险因素/大动脉粥样硬化/小血管病变/血压/血尿酸/甘油三酯Key words
Youth cerebral infarction/Risk factors/Large artery atherosclerosis/Blood pressure/Uric acid/Triglyceride分类
医药卫生引用本文复制引用
潘军利,周霭婷,徐嘉贺..青年脑梗死患者发病危险因素临床分析[J].中国实用神经疾病杂志,2018,21(2):133-135,139,4.基金项目
2013年中山市人民医院医学科研基金,编号:2013120 （）
