中国实用神经疾病杂志2018，Vol.21Issue(3)：253-257,5.DOI:10.12083/SYSJ.2018.03.065
红细胞分布宽度对急性脑梗死患者近期预后的预测价值
Red blood cell distribution width for the predictive analysis of the prognosis in patients with acute cerebral in-farction
摘要
Abstract
Objective To investigate the predictive value of red cell distribution width (RDW)for the short-term prognosis of acute cerebral infarction patients .Methods A total of 169 cases of acute cerebral infarction diagnosed at admission in the De-partment of Neurology ,the Fifth Affiliated Hospital of Zhengzhou University from January 2016 to March 2017 were enrolled ret-rospectively .They were divided into ether a good prognosis group (n=104) or a poor prognosis group (n=65) according to the scoring criteria of the modified Rankin scale (mRS) .The age ,gender ,past medical history ,National Institutes of Health stroke scale (NIHSS) score and RDW were collected on admission .Multivariate logistic regression analysis was used to analyze the risk factors of poor prognosis of acute cerebral infarction .Receiver operating characteristic curve (ROC) was used to evaluate the pre-dictive value of the RDW level for patients with acute cerebral infarction on admission .Results Compared with the good prognosis group ,NIHSS score on admission ,incidence of Diabetic history ,incidence of hyperlipidemia history and RDW levels on admission in the poor prognosis group were significantly higher[6(4 ,9)vs .3(2 ,6);44.6％ (29/65)vs .28.8％ (30/104);43.1％ (28/65) vs.26.0％ (27/104);14.2％ (13.5％ ,15.6％ )vs .13.5％ (12.7％ ,14.7％ );all P<0.05] .There were no significant differences in other indexes between the groups(all P>0.05) .Multivariate logistic regression analysis showed that the NIHSS score on admis-sion (OR 1.790 ,95％ CI were 1.388-2.309 ,P<0.001)and RDW level on admission(OR 1.629 ,95％ CI were 1.052-2.521 ,P<0.05) ,were independent risk factors for poor prognosis .ROC curve analysis showed that the diagnostic cut-off value of the RDW level on admission for the poor prognosis in patients with acute ischemic stroke was 13.65％ .Its sensitivity was 70.8％ and speci-ficity was 60.6％ .Conclusion Increased RDW at admission had certain reference function on the recent poor prognosis in patients with acute cerebral infarction .关键词
急性脑梗死/红细胞分布宽度/预后/Logistic回归分析/危险因素Key words
Acute cerebral infarction/Red cell distribution width/Prognosis/Logistic models/Risk factors分类
医药卫生引用本文复制引用
柯俊吉,王建平..红细胞分布宽度对急性脑梗死患者近期预后的预测价值[J].中国实用神经疾病杂志,2018,21(3):253-257,5.基金项目
国家自然科学基金项目(81571137) （81571137）
