中国实用神经疾病杂志2018，Vol.21Issue(3)：273-278,6.DOI:10.12083/SYSJ.2018.03.070
自身免疫性脑炎的临床分析及脑电图特点
Autoimmune encephalitis 9 cases of clinical feature analysis and electroencephalogram characteristics
摘要
Abstract
Objective To explore the characteristics of clinical manifestation ,magnetic resonance imaging (MRI) ,cerebro-spinal fluid(CSF) and treatment outcome of autoimmune encephalitis (AE) .Methods The clinical data of 9 patients with retro-spectively analyzed .Results Among these patients ,4 of them were proved to have anti-N-methyl-D-aspartate receptor (NMDA ) encephalitis ,while 1 of them got diagnosis of anti-leucine-rich glioma-inactivated protian 1 antibody(LG1) encephalitis ,and the other 2 had anti-γ-aminobutyric acid B receptor(GABAR) antibody .88.9％ of the patients had seizure ,66.7％ of the patients had involuntary movement and autonomic nerve dysfunction .44.4％ of the patients had abnormal CSF ,while 100％ of them showed abnormal in EEG ,22.2％ patients had abnormal MRI signal .8 patients accepted immunoglobulin therapy ,and 1 paitents returned to local hospital for treatment ,66.7％ of them had favorable prognosis .Conclusion Electroencephalogram is an important method to evaluate autoimmune encephalitis .关键词
自身免疫性脑炎/癫痫/σ刷/NMDAR脑炎/GABAR脑炎Key words
Autoimmune encephalitis/Seizures/δbrush/NMDAR/GABAR分类
医药卫生引用本文复制引用
黄明珠,陈丽真,陈圣根,车春晖,黄华品..自身免疫性脑炎的临床分析及脑电图特点[J].中国实用神经疾病杂志,2018,21(3):273-278,6.基金项目
国家自然基金面上项目(81371426) （81371426）
